ARN25068 是三种蛋白激酶GSK-3β、FYN和DYRK1A的亚微摩尔抑制剂，可解决 tau 蛋白过度磷酸化。
| 生物活性 | ARN25068 is a sub-micromolar inhibitor of the three protein kinases,GSK-3β, FYNandDYRK1Ato tackle tau hyperphosphorylation[1]. |
体外研究
(In Vitro) | ARN25068 reduces the extent of tau phosphorylation in Tau0N4R-TM-tGFP U2OS cell line. ARN25068 exhibits IC50values of 4.17 and 2.17 μM for GSK-3β and FYN in enzymatic radiometric assay, respectively[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
