RAF mutant-IN-1

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RAF mutant-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2340020-82-6

RAF mutant-IN-1 是RAF kinase的抑制剂，信息来自专利WO2019107987A1，对C-RAF^340D/Y341D、B-RAF^V600E和B-RAF^WT的IC₅₀值分别为 21 nM、30 nM和392 nM。

生物活性

RAFmutant-IN-1 is aRAFkinaseinhibitor, extracted from patent WO2019107987A1, withIC₅₀values of 21 nM, 30 nM and 392 nM forC-RAF^340D/Y341D, B-RAF^V600Eand B-RAF^WT, respectively^[1].

IC₅₀& Target

C-RAF^340D/Y341D

21 nM (IC₅₀)

B-Raf^V600E

30 nM (IC₅₀)

BRAF^WT

392 nM (IC₅₀)

分子量

567.85

Formula

C₂₃H₁₈Cl₃FN₆O₂S

CAS 号

2340020-82-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.