Mead ethanolamide

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Mead ethanolamide

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

169232-04-6

Mead ethanolamide 是一种内源性大麻素受体（cannabinoid receptor）激动剂，对CB1和CB2的K_d值分别为 753 nM 和 1810 nM。

生物活性

Mead ethanolamide is an endogenouscannabinoid receptoragonist withK_dvalues of 753 nM and 1810 nM againstCB1andCB2, respectively^[1].

IC₅₀& Target

CB1

753 nM (Kd)

CB2

1810 nM (Kd)

体外研究
(In Vitro)

Mead ethanolamide inhibits cAMP accumulation in CHO-hCB1 and CHO-hCB2 cells with IC₅₀s of 431 nM and 156 nM, respectively^[1].
Mead ethanolamide (1-1000 nM) inhibits N-type calcium currents in a concentration-dependent manner. Inhibition was halfmaximal at a Mead ethanolamide concentration of 124 ± 19 nM^[1].

分子量

349.55

Formula

C₂₂H₃₉NO₂

CAS 号

169232-04-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.