EZH2-IN-5 是一种有效的EZH2抑制剂，对野生型和突变型 Tyr641 EZH2 的IC50值分别为 1.52 nM 和 4.07 nM。
| 生物活性 | EZH2-IN-5 is a potentEZH2inhibitor withIC50values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641EZH2, respectively[1]. |
| IC50& Target[1] | EZH2 WT 1.52 nM (IC50) | EZH2 Y641F mutant type 4.07 nM (IC50) |
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体外研究
(In Vitro) | EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC50of 187.28 nM[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
