ROCK2-IN-5

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ROCK2-IN-5

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

ROCK2-IN-5 (compound 1d) 是一种混合化合物，含有 Rho 激酶抑制剂 fasudil 和 NRF2 诱导剂咖啡酸和阿魏酸的结构片段。ROCK2-IN-5 具有良好的多靶点分布和良好的耐受性。ROCK2-IN-5 有潜力用于具有 SOD1 突变的 ALS 研究。

生物活性

ROCK2-IN-5 (compound 1d) is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. ROCK2-IN-5 has good multitarget profile and good tolerability. ROCK2-IN-5 has the potential for thr research of Amyotrophic lateral sclerosis (ALS) with a SOD1 mutation^[1].

IC₅₀& Target^[1]

ROCK2

2.13 μM (IC₅₀)

分子量

455.53

Formula

C₂₃H₂₅N₃O₅S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.