MAL3-101 是一种有效的热休克蛋白 70 (HSP70) 变构抑制剂。MAL3-101 通过阻断 Hsp40 分子伴侣的相互作用来抑制 HSP70 ATP 酶活性。MAL3-101 可用于肌层浸润性膀胱癌的研究。
| 生物活性 | MAL3-101 is a potentHSP70allosteric inhibitor. MAL3-101 inhibitsHSP70ATPase activity by blockingHsp40co-chaperone interaction. MAL3-101 can be used for researching muscle invasive bladdercancer(MIBC)[1]. |
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体外研究
(In Vitro) | MAL3-101 (10 μM; 24, 48, 72 hours) induces cell viability in MIBC cell lines UMUC3, T24, SW780 and J82[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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