Peucedanocoumarin III 是一种 α-突触核蛋白(α-synuclein) 和亨廷顿蛋白聚集体抑制剂,增强了核和胞质 β23 聚集体的清除率,防止疾病相关蛋白(即突变亨廷顿蛋白和 α-突触核蛋白)诱导的细胞毒性。Peucedanocoumarin III 可用于帕金森疾病的研究。
| 生物活性 | Peucedanocoumarin III is an inhibitor of(alpha)-synucleinand Huntington protein aggregates that enhances the clearance of nuclear and cytoplasmic β23 aggregates and prevents cytotoxicity induced by disease-associated proteins (i.e., mutant Huntington proteins and α-synuclein). Peucedanocoumarin III may be used in Parkinson's disease research[1]. |
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| 结构分类 | - Phenylpropanoids
- Coumarins
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| 来源 | - Plants
- Umbelliferae
- Peucedanum japonicumThunb.
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |