LDHA/PDKs-IN-1 (compound 20e) 是一种有效的 PDKs 和 LDHA 双重抑制剂，IC50s 分别为 0.8 和 0.15 μM。LDHA/PDKs-IN-1 减少 A549 细胞增殖，EC50为 13.2 μM，减少乳酸形成，增加耗氧量。LDHA/PDKs-IN-1 具有研究癌症疾病的潜力。
| 生物活性 | LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA withIC50s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with anEC50of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research ofcancerdiseases[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
