基因名：
ULBP2
产品别名：
ALCAN-alpha； N2DL2； NKG2DL2； RAET1H； RAET1L； ULBP2； UL16 binding protein 2； UL16 binding protein 2； UL16-binding protein 2； NKG2D ligand 2； retinoic acid early transcript 1H； retinoic acid early transcript 1L； UL16结合蛋白2； UL16结合蛋白2(ULBP2)；
背景信息：
NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.
