基因名:
BIN2
产品别名:
BRAP-1; BIN2; bridging integrator 2; bridging integrator 2; bridging integrator 2; breast cancer associated protein BRAP1; breast cancer-associated protein 1; 乳腺癌相关蛋白1; 桥连整合因子2(BIN2);
背景信息:
Bridging Integrator 2 (BIN2) is a cytoplasmic protein. BIN2 contains one BAR domain and Interacts with BIN1. BIN2 is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. BIN2 is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling. Genetic studies show that BIN2 is inhibited in response to BR perception at the cell surface to relieve its inhibitory effects on downstream targets.