基因名：
LGALS3
产品别名：
CBP35； GAL3； GALBP； GALIG； L31； LGALS2； MAC2； LGALS3； galectin 3； galectin 3； galectin-3； 35 kDa lectin； IgE-binding protein； MAC-2 antigen； advanced glycation end-product receptor 3； carbohydrate-binding protein 35； epididymis secretory sperm binding protein； galactose-specific lectin 3； laminin-binding protein； lectin L-29； lectin, galactoside-binding, soluble, 3； 半乳糖凝集素3； 半乳糖凝集素3(GAL3)； 半乳糖凝集素3(GAL3)真核蛋白； 半乳糖凝集素3蛋白；
背景信息：
Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma, and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth, as a result providing a new mechanism for tumor immune tolerance.
