基因名:
H2AX
产品别名:
H2A.X; H2A/X; H2AFX; H2AX; H2A.X variant histone; H2A.X variant histone; histone H2AX; H2A histone family member X; H2AX histone; histone H2A.x; H2A组蛋白家族成员X(H2AFX); 泛素化组蛋白H2AX; 磷酸化组蛋白H2AX; 组蛋白H2AX;
背景信息:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008].