基因名：
CEACAM3
产品别名：
CD66D； CEA； CGM1； W264； W282； CEACAM3； CEA cell adhesion molecule 3； CEA cell adhesion molecule 3； carcinoembryonic antigen-related cell adhesion molecule 3； CD66d antigen； carcinoembryonic antigen CGM1； carcinoembryonic antigen gene family member 1； carcinoembryonic antigen related cell adhesion molecule 3； nonspecific cross-reacting antigen； 癌胚抗原相关细胞粘附分子3； 癌胚抗原相关细胞粘附分子3(CEACAM3)；
背景信息：
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3) belongs to the immunoglobulin superfamily and CEA family. CEACAM3 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM3 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, it is associated with the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
