靶标:
AMIGO1
产品别名:
ALI2; AMIGO; AMIGO-1; AMIGO1; adhesion molecule with Ig like domain 1; adhesion molecule with Ig like domain 1; amphoterin-induced protein 1; alivin-2; amphoterin-induced gene and ORF; Ig样域蛋白粘附分子1(AMIGO1); 粘附分子IgG样结构域蛋白1;
背景信息:
function:Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.,similarity:Belongs to the immunoglobulin superfamily. AMIGO family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with axons of neuronal cells.,subunit:Binds itself as well as AMIGO2 and AMIGO3.,