靶标:
GLS2
产品别名:
GA; GLS; LGA; hLGA; GLS2; glutaminase 2; glutaminase 2; glutaminase liver isoform, mitochondrial; L-glutamine amidohydrolase; breast cell glutaminase; glutaminase 2 (liver, mitochondrial); glutaminase I; phosphate-activated glutaminase; phosphate-dependent glutaminase; 谷氨酰胺酰胺水解酶; 谷氨酰胺酶2(GLS2);
背景信息:
Glutaminase 2 (liver, mitochondrial) is a protein that in humans is encoded by the GLS2 gene. The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms.