靶标：
PNPLA6
产品别名：
BNHS； LNMS； NTE； NTEMND； OMCS； SPG39； iPLA2delta； sws； PNPLA6； patatin like phospholipase domain containing 6； patatin like phospholipase domain containing 6； patatin-like phospholipase domain-containing protein 6； neuropathy target esterase； 含patatin样磷脂酶6； 神经疾病靶标酯酶(NTE)；
背景信息：
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
