Dihydrolycorine 是从 Lycoris radiate 草药中分离出来的，具有降压和神经保护作用。Dihydrolycorine 是真核细胞中 protein synthesis 的抑制剂。
货号:ajcx14422
CAS:6271-21-2
分子式:C16H19NO4
分子量：289.33
溶解度:DMSO: 3mg/mL,PBS (pH 7.2): 2.5mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Dihydrolycorine is isolated from Lycoris radiate Herb with antihypertensive and neuroprotective activities[1]. Dihydrolycorine is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step[2].

Dihydrolycorine reduces infarct size, cerebral edema, and myeloperoxidase activity in a rat model of focal cerebral ischemia-reperfusion injury when administered following reperfusion[1].Dihydrolycorine inhibits methoxamine-induced contraction of isolated rabbit aortic rings and rat anococcygeus muscle with pA2 values of 5.93 and 6.35, respectively[3].

[1]. JIANG Shi-qin, et al. Therapeutic Effects of Dihydrolycorine on Focal Cerebral Ischemia-reperfusion Injury in Rats. 《Journal of Yunyang Medical College》 2009-05 [2]. Jimenez A, et al. Inhibitors of protein synthesis in eukarytic cells. Comparative effects of some amaryllidaceae alkaloids. Biochim Biophys Acta. 1976 Mar 17;425(3):342-8. [3]. Chen BY, et al. [Hypotensive effect of dihydrolycorine]. Zhongguo Yao Li Xue Bao. 1993 Jan;14(1):45-9.