Bis-propargyl-PEG4 是一种用于合成 PORTAC 的 PROTAC linker，属于 PEG 类。Bis-propargyl-PEG2 被用于合成去甲万古霉素。
货号:ajcx35622
CAS:159428-42-9
分子式:C14H22O5
分子量：270.32
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers[1][2].

Bis-propargyl-PEG4 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].

[1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2.
[2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527-3533.