生物活性
Sodium orthovanadate是化合物Na3VO4。 它是蛋白质酪氨酸磷酸酶,碱性磷酸酶和许多ATPase的抑制剂,很可能充当磷酸盐类似物。
靶点信息
| (Na,K)-ATPase | Phosphatase | | | |
| 40 nM | 10 μM | | | |
化学数据
| 目录号 | A10854 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 183.9 |
| Formula | Na3O4V |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 13721-39-6 |
| SMILES | [O-][V](=O)([O-])[O-].[Na+].[Na+].[Na+] |
溶解度
| In vitro (25°C) | DMSO | Insoluble |
| Water | 32 mg/mL (173.99 mM) |
| Ethanol | Insoluble |
| In vivo | Saline | 28 mg/mL |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 54.38 mL | 271.89 mL | 543.77 mL |
| 0.5 mM | 10.88 mL | 54.38 mL | 108.75 mL |
| 1 mM | 5.44 mL | 27.19 mL | 54.38 mL |
| 5 mM | 1.09 mL | 5.44 mL | 10.88 mL |
*The above data is based on the productmolecular weight 183.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.