Gitoxin 是Na+/K+-ATPase的抑制剂,是Digitoxin 的降解代谢物,因ZOH 基团靠近C-17β 位置,可改善药代动力学和药效学数据。
| 生物活性 | Gitoxin, aNa+/K+-ATPaseinhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably[1]. |
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| 来源 | - Plants
- Scrophulariaceae
- Digitalis purpureaLinn.
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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