KRAS inhibitor-20 是一种KRasG12C致癌突变体的小分子抑制剂。KRAS inhibitor-20 抑制KRasG12C的 IC50<10 nM。
| 生物活性 | KRAS inhibitor-20 is a small molecular inhibitor ofKRasG12C, the oncogenic mutant. KRAS inhibitor-20 inhibitsKRasG12Cwith the IC50 value<10 nm[1]. |
| IC50& Target[1] | KRAS(G12C) <10 nM (IC50,[1]) |
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体外研究
(In Vitro) | KRAS inhibitor-20 (compound 12b) resultsKRasG12Calkylation human lung cancer adenocarcinoma (HCC 1171) with an EC50value of 3.3 nM[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
