EGLU

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EGLU

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

170984-72-2

(2S)-α-Ethylglutamic acid
(2S)-α-EGLU

EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) 是有效的竞争性mGluR-2受体拮抗剂。 EGLU 与 (lS,3S)-ACPD 敏感位点相互作用，K_d值为 66 μM。EGLU 是一种抗抑郁试剂。

生物活性

EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitivemGluR-2receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with aK_dvalue of 66 μM. EGLU is an antidepressant agent^[1].

IC₅₀& Target

mGluR2

66 μM (Kd)

体外研究
(In Vitro)

EGLU (200 μM) selectively antagonizes (lS,3S)-ACPD-induced depressions of the monosynaptic component of the DRVRP, displaying little or no antagonist activity versus L-AP6 induced depressions or on the DRVRP alone^[1].

分子量

175.18

Formula

C₇H₁₃NO₄

CAS 号

170984-72-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.