MK-571 (L-660711) is a novel, potent, selective, orally bioactive antagonist of leukotriene D4 (LTD4) receptor with Kis of 0.22 and 2.1 nM in guinea pig and human lung membranes. MK-571 blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively. MK-571 attenuates kidney ischemia and reperfusion-induced airway hypersensitivity in rats. MK-571 alters bronchoalveolar lavage fluid proteome in a mouse asthma model.

纯度：≥98%

CAS：115104-28-4