Otlertuzumab

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Otlertuzumab

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1372645-37-8

TRU-016

Otlertuzumab (TRU-016) 是一种人源化抗CD37单克隆抗体，可用于癌症研究。

生物活性

Otlertuzumab (TRU-016) is a humanized anti-CD37monoclonal antibody that can be used forcancerresearch^[1].

IC₅₀& Target

CD37^[1]

体外研究
(In Vitro)

Otlertuzumab (TRU-016) in combination withRituximab(HY-P9913),Rapamycin(HY-10219), orBendamustine(HY-13567) increases cell killing of NHL cells^[2].
Otlertuzumab has the ability to bind to and kill CD37⁺cells^[3].

体内研究
(In Vivo)

Otlertuzumab (TRU-016) in combination withBendamustine(HY-13567) displays greater anti-tumor activity than either agent alone against a follicular lymphoma tumor model in SCID mice^[2].
Otlertuzumab shows significant antitumor activity in mice bearing Ramos or Daudi tumor xenografts^[3].

Clinical Trial

CAS 号

1372645-37-8

中文名称

奥乐妥珠单抗

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.