CU067_HUMAN
ID CU067_HUMAN Reviewed; 204 AA.
AC P58512; P58556; Q495D3; Q495D5;
DT 23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2002, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Uncharacterized protein encoded by LINC01547 {ECO:0000312|HGNC:HGNC:15707};
GN Name=LINC01547 {ECO:0000312|HGNC:HGNC:15707};
GN Synonyms=C21orf67 {ECO:0000312|HGNC:HGNC:15707},
GN C21orf69 {ECO:0000312|HGNC:HGNC:15707};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), AND NUCLEOTIDE SEQUENCE
RP [MRNA] OF 152-204 (ISOFORM 3).
RX PubMed=11707072; DOI=10.1006/geno.2001.6640;
RA Reymond A., Friedli M., Neergaard Henrichsen C., Chapot F., Deutsch S.,
RA Ucla C., Rossier C., Lyle R., Guipponi M., Antonarakis S.E.;
RT "From PREDs and open reading frames to cDNA isolation: revisiting the human
RT chromosome 21 transcription map.";
RL Genomics 78:46-54(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10830953; DOI=10.1038/35012518;
RA Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S.,
RA Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M.,
RA Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A., Menzel U.,
RA Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A.,
RA Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J.,
RA Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K.,
RA Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G.,
RA Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J.,
RA Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S.,
RA Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K.,
RA Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.;
RT "The DNA sequence of human chromosome 21.";
RL Nature 405:311-319(2000).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1; Synonyms=A;
CC IsoId=P58512-1; Sequence=Displayed;
CC Name=2; Synonyms=B;
CC IsoId=P58512-2; Sequence=VSP_003829, VSP_003830;
CC Name=3;
CC IsoId=P58512-3; Sequence=VSP_039828, VSP_039829;
CC -!- TISSUE SPECIFICITY: Not detected in any tissue tested.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK60445.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
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DR EMBL; AF380178; AAL34496.1; -; mRNA.
DR EMBL; AY035381; AAK60445.1; ALT_SEQ; mRNA.
DR EMBL; AY040088; AAK74136.1; -; mRNA.
DR EMBL; AL844908; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P58512; -.
DR IntAct; P58512; 1.
DR BioMuta; HGNC:15707; -.
DR PaxDb; P58512; -.
DR PeptideAtlas; P58512; -.
DR PRIDE; P58512; -.
DR GeneCards; LINC01547; -.
DR HGNC; HGNC:15707; LINC01547.
DR neXtProt; NX_P58512; -.
DR InParanoid; P58512; -.
DR ChiTaRS; LINC01547; human.
DR Pharos; P58512; Tdark.
DR PRO; PR:P58512; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; P58512; protein.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:UniProtKB.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..204
FT /note="Uncharacterized protein encoded by LINC01547"
FT /id="PRO_0000079526"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..22
FT /note="MGWDCRRTTVENPSPIRNCVNQ -> MARNRLIAASTSRTRAILPPQPLEK
FT (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:11707072"
FT /id="VSP_039828"
FT VAR_SEQ 72..82
FT /note="LAADLAGDALP -> CTSGASAGQKL (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:11707072"
FT /id="VSP_003829"
FT VAR_SEQ 83..204
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:11707072"
FT /id="VSP_003830"
FT VAR_SEQ 165..204
FT /note="GGFPACLPAPKSSTDSASSCFKGGREFSDPLDIPGAGAMG -> GFPVSWRT
FT RMRAFHLSLPGGAQLLTYLVKVLKRRTWRRNVDNNPGCLCVPS (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:11707072"
FT /id="VSP_039829"
FT CONFLICT 158
FT /note="W -> R (in Ref. 1; AAK60445)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 204 AA; 21308 MW; F955EC4E414F2340 CRC64;
MGWDCRRTTV ENPSPIRNCV NQEWPEGSSP GLTEGNTGLV RDLRPAHQDR SGTREDPAGQ
ETTAITNPSP SLAADLAGDA LPGCLGAAAH QGPLLDRSSE STLGPQALEL EHCHERGCCR
GCASFSPFPA PRCPSERLGA HSSRWAIRGR SKINPPPWAP ACLPGGFPAC LPAPKSSTDS
ASSCFKGGRE FSDPLDIPGA GAMG
