ID   CSRP1_BOVIN             Reviewed;         193 AA.
AC   Q3MHY1;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Cysteine and glycine-rich protein 1;
DE   AltName: Full=Cysteine-rich protein 1;
DE            Short=CRP1;
GN   Name=CSRP1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Ascending colon;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Could play a role in neuronal development. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with ASCC1; ASCC2 AND TRIP4.
CC       {ECO:0000250|UniProtKB:P21291}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P21291}.
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DR   EMBL; BC104539; AAI04540.1; -; mRNA.
DR   RefSeq; NP_001077240.1; NM_001083771.1.
DR   AlphaFoldDB; Q3MHY1; -.
DR   SMR; Q3MHY1; -.
DR   IntAct; Q3MHY1; 1.
DR   STRING; 9913.ENSBTAP00000021369; -.
DR   PaxDb; Q3MHY1; -.
DR   PeptideAtlas; Q3MHY1; -.
DR   PRIDE; Q3MHY1; -.
DR   Ensembl; ENSBTAT00000021369; ENSBTAP00000021369; ENSBTAG00000016057.
DR   GeneID; 615329; -.
DR   KEGG; bta:615329; -.
DR   CTD; 1465; -.
DR   VEuPathDB; HostDB:ENSBTAG00000016057; -.
DR   VGNC; VGNC:27773; CSRP1.
DR   eggNOG; KOG1700; Eukaryota.
DR   GeneTree; ENSGT00940000156777; -.
DR   HOGENOM; CLU_054591_1_0_1; -.
DR   InParanoid; Q3MHY1; -.
DR   OMA; VQCEGHS; -.
DR   OrthoDB; 1214165at2759; -.
DR   TreeFam; TF313758; -.
DR   Proteomes; UP000009136; Chromosome 16.
DR   Bgee; ENSBTAG00000016057; Expressed in trachea and 105 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0030018; C:Z disc; IBA:GO_Central.
DR   GO; GO:0042805; F:actinin binding; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008307; F:structural constituent of muscle; IBA:GO_Central.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:GO_Central.
DR   GO; GO:0060537; P:muscle tissue development; IBA:GO_Central.
DR   GO; GO:0045214; P:sarcomere organization; IBA:GO_Central.
DR   InterPro; IPR001781; Znf_LIM.
DR   Pfam; PF00412; LIM; 2.
DR   SMART; SM00132; LIM; 2.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 2.
PE   2: Evidence at transcript level;
KW   Acetylation; LIM domain; Metal-binding; Nucleus; Phosphoprotein;
KW   Reference proteome; Repeat; Zinc.
FT   CHAIN           1..193
FT                   /note="Cysteine and glycine-rich protein 1"
FT                   /id="PRO_0000075714"
FT   DOMAIN          10..61
FT                   /note="LIM zinc-binding 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   DOMAIN          119..170
FT                   /note="LIM zinc-binding 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   MOTIF           64..69
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         81
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P47875"
FT   MOD_RES         84
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P97315"
FT   MOD_RES         112
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P21291"
FT   MOD_RES         131
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P21291"
FT   MOD_RES         137
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P97315"
FT   MOD_RES         161
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P97315"
FT   MOD_RES         192
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21291"
SQ   SEQUENCE   193 AA;  20612 MW;  D8FADEFD582B4AFC CRC64;
     MPNWGGGKKC GVCQKTVYFA EEVQCEGSSF HKSCFLCLVC KKNLDSTTVA VHGEEIYCKS
     CYGKKYGPKG YGYGQGAGTL SMDKGESLGI RHEEAPGHRP TTNPNTSKFA QKVGGSERCP
     RCSQAVYAAE KVIGAGKSWH KSCFRCAKCG KGLESTTLAD KDGEIYCKGC YAKNFGPKGF
     GFGQGAGALV HSE