COPA3_ORYSJ
ID COPA3_ORYSJ Reviewed; 1218 AA.
AC Q0J3D9; A0A0P0XK16;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Coatomer subunit alpha-3;
DE AltName: Full=Alpha-coat protein 3;
DE Short=Alpha-COP 3;
GN OrderedLocusNames=Os09g0127800, LOC_Os09g04110; ORFNames=OsJ_027299;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: The coatomer is a cytosolic protein complex that binds to
CC dilysine motifs and reversibly associates with Golgi non-clathrin-
CC coated vesicles, which further mediate biosynthetic protein transport
CC from the ER, via the Golgi up to the trans Golgi network. Coatomer
CC complex is required for budding from Golgi membranes, and is essential
CC for the retrograde Golgi-to-ER transport of dilysine-tagged proteins
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Oligomeric complex that consists of at least the alpha, beta,
CC beta', gamma, delta, epsilon and zeta subunits. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Golgi apparatus membrane
CC {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic
CC side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane
CC {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic
CC side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on
CC the cytoplasmic side of the Golgi, as well as on the vesicles/buds
CC originating from it. {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK103786; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
CC Sequence=AK103786; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AP008215; BAF24526.1; -; Genomic_DNA.
DR EMBL; AP014965; BAT06915.1; -; Genomic_DNA.
DR EMBL; CM000146; EAZ43816.1; -; Genomic_DNA.
DR EMBL; AK103786; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015611836.1; XM_015756350.1.
DR AlphaFoldDB; Q0J3D9; -.
DR SMR; Q0J3D9; -.
DR STRING; 4530.OS09T0127800-01; -.
DR iPTMnet; Q0J3D9; -.
DR PaxDb; Q0J3D9; -.
DR PRIDE; Q0J3D9; -.
DR EnsemblPlants; Os09t0127800-01; Os09t0127800-01; Os09g0127800.
DR GeneID; 4346440; -.
DR Gramene; Os09t0127800-01; Os09t0127800-01; Os09g0127800.
DR KEGG; osa:4346440; -.
DR eggNOG; KOG0292; Eukaryota.
DR HOGENOM; CLU_007565_1_0_1; -.
DR InParanoid; Q0J3D9; -.
DR OMA; ICAEYIV; -.
DR OrthoDB; 139008at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000007752; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR ExpressionAtlas; Q0J3D9; baseline and differential.
DR Genevisible; Q0J3D9; OS.
DR GO; GO:0030126; C:COPI vesicle coat; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR016391; Coatomer_asu.
DR InterPro; IPR010714; Coatomer_asu_C.
DR InterPro; IPR006692; Coatomer_WD-assoc_reg.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011048; Haem_d1_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF04053; Coatomer_WDAD; 1.
DR Pfam; PF06957; COPI_C; 1.
DR Pfam; PF00400; WD40; 5.
DR PIRSF; PIRSF003354; Coatomer_alpha_subunit; 1.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR SUPFAM; SSF51004; SSF51004; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoplasmic vesicle; ER-Golgi transport; Golgi apparatus;
KW Membrane; Protein transport; Reference proteome; Repeat; Transport;
KW WD repeat.
FT CHAIN 1..1218
FT /note="Coatomer subunit alpha-3"
FT /id="PRO_0000285603"
FT REPEAT 7..48
FT /note="WD 1"
FT REPEAT 49..88
FT /note="WD 2"
FT REPEAT 91..132
FT /note="WD 3"
FT REPEAT 133..172
FT /note="WD 4"
FT REPEAT 202..241
FT /note="WD 5"
FT REPEAT 246..285
FT /note="WD 6"
FT REPEAT 288..326
FT /note="WD 7"
FT REPEAT 363..404
FT /note="WD 8"
FT REPEAT 450..489
FT /note="WD 9"
FT REGION 854..893
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..886
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 540
FT /note="N -> Y (in Ref. 5; AK103786)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1218 AA; 136564 MW; 4E82B471E7EE15B6 CRC64;
MLTKFETKSN RVKGLSFHPR RPWILASLHS GVIQMWDYRM GTLLDRFDEH DGPVRGVHFH
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW
NWQSRTCVAV LTGHNHYVMC ASFHPKEDLV VSASLDQTVR VWDIGALRKK TVSPADDILR
LTQMNTDLFG GVDAVVKYVL EGHDRGVNWA SFHPTLPLIV SGADDRQVKL WRMNDTKAWE
VDTLRGHMNN VSCVMFHAKQ DIIVSNSEDK SIRVWDATKR TGIQTFRREH DRFWILAAHP
EMNLLAAGHD NGMIVFKLER ERPAFSVSGD TVFYVKDRFL RFFEYSTQKE VQLAPIRRPG
SVSLNQSPRT LSYSPTENAV LICSDVDGGS YELYIVPKDS AGRTDYLQEA KKGAGGSAVF
VARNRFAVLE KSSNQVLVKN LKNEIVKKSP LPIAMDAIYY AGTGNLLCKA EDRVTIFDLQ
QRLILGELQA PAVKYVVWSS DMESIALLSK HAVVIANKKL VHRCTLHETI RVKSGAWDEN
GVFIYTTLNH IKYCLPNGDS GIIKTLDVPI YITRAIGNNI FCLDRDGKNK LITVDASEYI
FKLALLRKRY DHVMSMIKNS QLCGQAVISY LQQKGFPEVA LHFVKDEKTR FNLALESGNI
QIAVASAKEI DDKDHWYRLG IEALRQGNVG IVEYAYQRTK NFERLAFLYL ITGYMDKVGF
MCKIAGQNNN LMGQFHNALY LGDAMKRVEI LENAGQLPLA YITAATHGLT EIADRLAAEL
GENIPSLPEG KTRSLLIPPA PLTASGDWPL LRVMRGIFEG GLDATGKAEL EEDDEAAGAD
WGDEDLDMVD ASEAMANGGD GFDAEEGEAN EEDGEEGGWD LEDLELPPEA ETPKNAGNAL
SVVFVAPPPG MPVSQIWTQK SSLAGEHAAA GNFDTAMRLL SRQLGIKNFA PLKPLFLDLH
MGSHSYLRAL ATAPIIPVAV EKGWSESASP NVRGPPALVF TFSQMEDRLK AAYKATTEGK
FPEALRQFLN ILHTIPLIVV DSRREVDEVK ELIEIVREYV LGLRMELKRK ELRDDVNRQQ
ELAAYFTNCK LQRVHMRLVL GSAMGLCYKQ KNFATAEHFA RMLLENNPNE SQAKRARQVQ
QQCSGKKDSC ELNYDYRNPF VVCGATYVPI YRGQKDVSCP YCGSRFVPSI EGQLCTICEL
AVVGADASGL LCSPTQLR
