ID   COG4_SCHPO              Reviewed;         738 AA.
AC   O74990;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 4;
DE            Short=COG complex subunit 4;
DE   AltName: Full=Component of oligomeric Golgi complex 4;
GN   Name=cog4; ORFNames=SPCC338.13;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Component of the peripheral membrane COG complex that is
CC       involved in intra-Golgi protein trafficking. COG is located at the cis-
CC       Golgi, and regulates tethering of retrograde intra-Golgi vesicles and
CC       possibly a number of other membrane trafficking events (By similarity).
CC       {ECO:0000250|UniProtKB:Q06096}.
CC   -!- SUBUNIT: Component of the conserved oligomeric Golgi complex.
CC       {ECO:0000250|UniProtKB:Q06096}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q9H9E3}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:Q9H9E3}; Cytoplasmic side
CC       {ECO:0000250|UniProtKB:Q9H9E3}.
CC   -!- SIMILARITY: Belongs to the COG4 family. {ECO:0000305}.
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DR   EMBL; CU329672; CAA19344.1; -; Genomic_DNA.
DR   PIR; T41730; T41730.
DR   RefSeq; NP_588155.1; NM_001023144.2.
DR   AlphaFoldDB; O74990; -.
DR   SMR; O74990; -.
DR   BioGRID; 275590; 5.
DR   IntAct; O74990; 1.
DR   STRING; 4896.SPCC338.13.1; -.
DR   MaxQB; O74990; -.
DR   PaxDb; O74990; -.
DR   EnsemblFungi; SPCC338.13.1; SPCC338.13.1:pep; SPCC338.13.
DR   GeneID; 2539017; -.
DR   KEGG; spo:SPCC338.13; -.
DR   PomBase; SPCC338.13; cog4.
DR   VEuPathDB; FungiDB:SPCC338.13; -.
DR   eggNOG; KOG0412; Eukaryota.
DR   HOGENOM; CLU_014853_3_1_1; -.
DR   InParanoid; O74990; -.
DR   OMA; SECQQRV; -.
DR   PhylomeDB; O74990; -.
DR   PRO; PR:O74990; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0032153; C:cell division site; HDA:PomBase.
DR   GO; GO:0051286; C:cell tip; HDA:PomBase.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; ISO:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0006886; P:intracellular protein transport; IC:PomBase.
DR   GO; GO:0000301; P:retrograde transport, vesicle recycling within Golgi; ISO:PomBase.
DR   InterPro; IPR013167; COG_su4.
DR   Pfam; PF08318; COG4; 1.
DR   SMART; SM00762; Cog4; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..738
FT                   /note="Conserved oligomeric Golgi complex subunit 4"
FT                   /id="PRO_0000339132"
SQ   SEQUENCE   738 AA;  85350 MW;  8C193F4B6A14BC6B CRC64;
     MDISINDCTD ISQIKQRFHD LQVESQRTDE KLERLLSDAQ PTEKFNSLIK NMAERLVLFV
     GQIEELKDAF CNTTIVSEEV IERIKSVDRE QNRIKECLLF VRQVRDFKEC LQDLNRAMHH
     QQWEKAADLV HRASSTSPAI IEGKFAHAVV PTAEQPLAPM DTLKEITESL HTLFWREFHK
     AARNQDQKEI TRYFKLFPLI GKEKEGLEAY WHFFGGIIAS KARATLDEPP THALFFAQAF
     TGLVEHVASI IRAHTPLVQK YYKAKNTITV IEKLQGDCDR QGSIIVNTMF DVRRIDNLVS
     SIASYKYILL HAKLKNRAFV SDQKELERVS LQTLHPILNE MSAIVSKWNI SKIFISRLVL
     RLSQSDGTSN DPSVQDNLIC ASIFNSSKME LLLKKQLLPS LLQLETYYFR RSIETSLELE
     EYYTKVSPWM SSIVDDVMYV TKQVFQRAFF TVSSLFFTRF VNESLIPILR NDYYVYLSHN
     LLTVCNIIKA QFQRLKNANS IPAKQVENYI TLVNSASLSK QYLKSIVDGV SSRLEEVFAF
     AKDQKLVKKS IDNFLQLTVN FENLCKTSFN MYFPIFLLPR IEQCIDDSFD GINYVLSYED
     YTKETEHERL VVTRLRSVWD RVLLLEQFTP ENQLSLRSMA CEKAASYIEN LILYKIQWND
     YGAMALENDI SSLITIFSND QANLRHSFER LQEILILLVW ESDSTAPEQL INDLNLQLLS
     IDIVSAIMEK KANVQGED