ID   COG3_DICDI              Reviewed;         925 AA.
AC   Q54TT4;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 3;
DE            Short=COG complex subunit 3;
DE   AltName: Full=Component of oligomeric Golgi complex 3;
GN   Name=cog3; ORFNames=DDB_G0281511;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Required for normal Golgi function. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC       composed of eight different subunits and is required for normal Golgi
CC       morphology and localization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG3 family. {ECO:0000305}.
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DR   EMBL; AAFI02000041; EAL66737.1; -; Genomic_DNA.
DR   RefSeq; XP_640727.1; XM_635635.1.
DR   AlphaFoldDB; Q54TT4; -.
DR   STRING; 44689.DDB0237869; -.
DR   PaxDb; Q54TT4; -.
DR   EnsemblProtists; EAL66737; EAL66737; DDB_G0281511.
DR   GeneID; 8623116; -.
DR   KEGG; ddi:DDB_G0281511; -.
DR   dictyBase; DDB_G0281511; cog3.
DR   eggNOG; KOG2604; Eukaryota.
DR   HOGENOM; CLU_011639_1_1_1; -.
DR   InParanoid; Q54TT4; -.
DR   OMA; LDEFELW; -.
DR   PhylomeDB; Q54TT4; -.
DR   Reactome; R-DDI-6807878; COPI-mediated anterograde transport.
DR   Reactome; R-DDI-6811438; Intra-Golgi traffic.
DR   PRO; PR:Q54TT4; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005801; C:cis-Golgi network; IEA:InterPro.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   InterPro; IPR007265; COG_su3.
DR   PANTHER; PTHR13302; PTHR13302; 1.
DR   Pfam; PF04136; Sec34; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..925
FT                   /note="Conserved oligomeric Golgi complex subunit 3"
FT                   /id="PRO_0000341682"
FT   REGION          68..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          416..446
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          863..925
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   925 AA;  107427 MW;  2BA993CC68191F51 CRC64;
     MNNQTNQQSQ TQSQSQQRIN FDITGWEKKS KLSTQQYLLI NNLNKSTQEK PLPQKYLEDK
     INNDIKKEEN QQLQQQQQQQ QQQQQQQQSP IIENFMDNFN PKTDIDNLSD FYQWYSIIDK
     NNPHLHQYEW FLETIVNYSK GSNQLLSMVE NCDKLVESIQ TDYSNLTKKT NQLNEDCEKF
     FNEELKLRYI AQSIHDKLKF YNQLEIQTKK FNTTNFNVTD STFLTSLENL ENSINFMKSN
     STFMESNKYL TQYGFIFSRA LGLIKDYISS NLKILSRDII NAQKQLKTSV STPTSPQLQS
     SSGGSPLIND FSNSTDFNDL FQHSNIRFRA FAPKLRPLCL ELEKRAIGPY LSYLYDTQNI
     YFNNRRSILS LIMFEKLQSL SKMTDISSMI RSSSLFMIQF YENEYQIYSN FFSPPDLNNN
     NNNNNNNNNN DNINNSTNIN NSNNTNNNNQ DIINNCPAFS NILDEYSQQL YDTIRPIYIH
     IHSFETLCNL AHLIRNELID DLVQKSMKYS NGFKMTIERM LQDIQERLIF IIQTYIRDEI
     RSYHPNSDDL DYPNKLKIYV TAESTAVDGD GNGSGNSSPT LSYKSIYSTW YPTLEKSLTC
     LSKLYLVLET RIFEGLAQEV VEACTFTLIQ ASRLLLIQQK NDPYIILDSQ LFLIKNLLTL
     REQIAPFDIN FVIIEKIVDF PNLKHSLSTL YNVGSFLTLS TNNPILSLLS PRVTNTSIDS
     KKDLEKELKQ SIESFILSNA NTIIDPLLSL LTKISVFLNQ SNKNQTDPML LSQQSFADPQ
     RIKEIIEQVK EKASNYLPQV IDRMKLYLSI STQILLMKPI RTNIIDSFDQ INQYTKKYYT
     EDQIKIIDLQ SLKLILDKIL TPSKQSNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     NNKNENNENE NENNSNVNSP SPQQL