ID   CLN5A_DICDI             Reviewed;         378 AA.
AC   Q86JG6; Q55AV4;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Cln5-like protein 1;
DE   Flags: Precursor;
GN   Name=cln5la; ORFNames=DDB_G0271546;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CLN5 family. {ECO:0000305}.
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DR   EMBL; AAFI02000006; EAL71637.1; -; Genomic_DNA.
DR   RefSeq; XP_645592.1; XM_640500.1.
DR   AlphaFoldDB; Q86JG6; -.
DR   SMR; Q86JG6; -.
DR   PaxDb; Q86JG6; -.
DR   EnsemblProtists; EAL71637; EAL71637; DDB_G0271546.
DR   GeneID; 8618047; -.
DR   KEGG; ddi:DDB_G0271546; -.
DR   dictyBase; DDB_G0271546; -.
DR   eggNOG; ENOG502RBPB; Eukaryota.
DR   HOGENOM; CLU_062132_0_0_1; -.
DR   InParanoid; Q86JG6; -.
DR   OMA; ICNDFVW; -.
DR   PhylomeDB; Q86JG6; -.
DR   PRO; PR:Q86JG6; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005765; C:lysosomal membrane; IBA:GO_Central.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IBA:GO_Central.
DR   GO; GO:0007040; P:lysosome organization; IBA:GO_Central.
DR   InterPro; IPR018939; Autophagy-rel_prot_27.
DR   InterPro; IPR026138; CLN5.
DR   PANTHER; PTHR15380; PTHR15380; 1.
DR   Pfam; PF09451; ATG27; 1.
DR   Pfam; PF15014; CLN5; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..378
FT                   /note="Cln5-like protein 1"
FT                   /id="PRO_0000330474"
FT   TRANSMEM        308..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        63
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        93
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        135
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        181
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        220
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        226
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        254
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        280
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   378 AA;  42307 MW;  2CF33D60851FD036 CRC64;
     MNKIIIFILF LISILQSVRG FTDTDEIVVL YLEAPLFFSK FGTLLANVNA FHSGLGFYSL
     NSNETYQVDF VAVPGVLESI LPNKIENGEI IWNTSGKVQF SDSIDNTGYW SSEKEIMTIN
     NEIFETFLCW AQNYNESLSY YQLFDVLNRN TNELLVKSVV CNDFVWAGFN ALYNLGGKYI
     NDSIIASRDI VTLYTRESIE YVQDGSTNIE VISFYEAMLN ISIPKNQTIN GLIEELDELF
     KGNFYLYVNG DYYNVTLDSS PFSFAYSESP LPIGERDLSN ITLLESCHFQ HSSDNDIILN
     NKNGIGGWIF IIILLSFTTV YLVGGILINK FKNEKSGLDL IPNKDSWSSL GGLISDGFGF
     IKSKATGSTS GGNGYSSI