CLC87_CAEEL
ID CLC87_CAEEL Reviewed; 233 AA.
AC Q9XVS3;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=C-type lectin domain-containing protein 87;
DE AltName: Full=Chondroitin proteoglycan 5;
DE Flags: Precursor;
GN Name=clec-87 {ECO:0000312|EMBL:CAB02756.1, ECO:0000312|WormBase:C25A1.8};
GN Synonyms=cpg-5 {ECO:0000312|EMBL:ABC65815.1}; ORFNames=C25A1.8;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1] {ECO:0000305, ECO:0000312|EMBL:ABC65815.1}
RP NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION BY MASS SPECTROMETRY, AND
RP GLYCOSYLATION AT SER-31.
RX PubMed=16785326; DOI=10.1083/jcb.200603003;
RA Olson S.K., Bishop J.R., Yates J.R., Oegema K., Esko J.D.;
RT "Identification of novel chondroitin proteoglycans in Caenorhabditis
RT elegans: embryonic cell division depends on CPG-1 and CPG-2.";
RL J. Cell Biol. 173:985-994(2006).
RN [2] {ECO:0000312|EMBL:CAB02756.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [3] {ECO:0000305}
RP GLYCOSYLATION AT ASN-81, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=Bristol N2;
RX PubMed=12754521; DOI=10.1038/nbt829;
RA Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA Kasai K., Takahashi N., Isobe T.;
RT "Lectin affinity capture, isotope-coded tagging and mass spectrometry to
RT identify N-linked glycoproteins.";
RL Nat. Biotechnol. 21:667-672(2003).
RN [4]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-81, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=Bristol N2;
RX PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA Taoka M., Takahashi N., Isobe T.;
RT "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT elegans and suggests an atypical translocation mechanism for integral
RT membrane proteins.";
RL Mol. Cell. Proteomics 6:2100-2109(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQ340627; ABC65815.1; -; mRNA.
DR EMBL; Z81038; CAB02756.1; -; Genomic_DNA.
DR PIR; T19432; T19432.
DR RefSeq; NP_492682.1; NM_060281.4.
DR AlphaFoldDB; Q9XVS3; -.
DR SMR; Q9XVS3; -.
DR BioGRID; 38304; 1.
DR STRING; 6239.C25A1.8; -.
DR iPTMnet; Q9XVS3; -.
DR EPD; Q9XVS3; -.
DR PaxDb; Q9XVS3; -.
DR PeptideAtlas; Q9XVS3; -.
DR EnsemblMetazoa; C25A1.8.1; C25A1.8.1; WBGene00007709.
DR GeneID; 172885; -.
DR KEGG; cel:CELE_C25A1.8; -.
DR UCSC; C25A1.8; c. elegans.
DR CTD; 172885; -.
DR WormBase; C25A1.8; CE08374; WBGene00007709; clec-87.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT00970000196041; -.
DR HOGENOM; CLU_093598_0_0_1; -.
DR InParanoid; Q9XVS3; -.
DR OMA; CYWIETE; -.
DR OrthoDB; 1197324at2759; -.
DR PhylomeDB; Q9XVS3; -.
DR PRO; PR:Q9XVS3; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00007709; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IBA:GO_Central.
DR Gene3D; 3.10.100.10; -; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF56436; SSF56436; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE 1: Evidence at protein level;
KW Disulfide bond; Glycoprotein; Lectin; Proteoglycan; Reference proteome;
KW Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..233
FT /note="C-type lectin domain-containing protein 87"
FT /evidence="ECO:0000255"
FT /id="PRO_0000320338"
FT DOMAIN 93..223
FT /note="C-type lectin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT CARBOHYD 31
FT /note="O-linked (Xyl...) (chondroitin sulfate) serine"
FT /evidence="ECO:0000269|PubMed:16785326"
FT CARBOHYD 81
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000269|PubMed:12754521,
FT ECO:0000269|PubMed:17761667"
FT CARBOHYD 225
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 114..222
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT DISULFID 193..214
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
SQ SEQUENCE 233 AA; 26764 MW; 3746522165341C81 CRC64;
MRFCLLVAFI LPGLFLVHAA PTSSTELPEA SGEAPETSPL VQNDEQPHQR LTFYNWDYKD
LGTTAFEDIS FPARQPPAFV NQTEKCPDGW LRFADSCYWI EKELLGFAKA ERNCFEKQST
LFVANSIEEW DAIRVQAKEA FFSWIGLVRF THYEKLEQLP RWQTEGALNP TKINWLIKPY
KPLFNGWSSL ANCAASYKSP SSLESASYTY FYPCTYMLYS ICERNSTIVN ALQ
