ID   CF120_RAT               Reviewed;         185 AA.
AC   Q6AY64;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=UPF0669 protein C6orf120 homolog;
DE   Flags: Precursor;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May be involved in induction of apoptosis in CD4(+) T-cells,
CC       but not CD8(+) T-cells or hepatocytes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Note=Secreted by
CC       hepatocytes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0669 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC079175; AAH79175.1; -; mRNA.
DR   RefSeq; NP_001096826.1; NM_001103356.2.
DR   RefSeq; XP_006228031.1; XM_006227969.3.
DR   RefSeq; XP_006228032.1; XM_006227970.2.
DR   AlphaFoldDB; Q6AY64; -.
DR   STRING; 10116.ENSRNOP00000020889; -.
DR   GlyGen; Q6AY64; 1 site.
DR   PaxDb; Q6AY64; -.
DR   Ensembl; ENSRNOT00000095112; ENSRNOP00000080983; ENSRNOG00000070184.
DR   Ensembl; ENSRNOT00000108772; ENSRNOP00000093357; ENSRNOG00000070184.
DR   GeneID; 100125364; -.
DR   KEGG; rno:100125364; -.
DR   UCSC; RGD:1642424; rat.
DR   RGD; 1642424; LOC100125364.
DR   VEuPathDB; HostDB:ENSRNOG00000015609; -.
DR   eggNOG; ENOG502RXJP; Eukaryota.
DR   GeneTree; ENSGT00390000018879; -.
DR   HOGENOM; CLU_113576_1_0_1; -.
DR   InParanoid; Q6AY64; -.
DR   OMA; ESIFWTI; -.
DR   OrthoDB; 1394242at2759; -.
DR   PhylomeDB; Q6AY64; -.
DR   TreeFam; TF331743; -.
DR   Reactome; R-RNO-6798695; Neutrophil degranulation.
DR   PRO; PR:Q6AY64; -.
DR   Proteomes; UP000002494; Chromosome 1.
DR   Bgee; ENSRNOG00000015597; Expressed in pancreas and 20 other tissues.
DR   Genevisible; Q6AY64; RN.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   InterPro; IPR031420; UPF0669.
DR   PANTHER; PTHR31703; PTHR31703; 1.
DR   Pfam; PF17065; UPF0669; 1.
PE   2: Evidence at transcript level;
KW   Apoptosis; Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..185
FT                   /note="UPF0669 protein C6orf120 homolog"
FT                   /id="PRO_0000297665"
FT   CARBOHYD        47
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   185 AA;  20903 MW;  73EECAA100947842 CRC64;
     MATPWRCALL MILASQVVIL VKCLEDDDVP EEWLLLHVVQ GQIGAGNYSY LRLNHEGKII
     LRMQSLRGDA DLYVSDSTPH PSFDEYELQS VTCGQDVVSI PAHFQRPVGI GIYGHPSHHE
     SDFEMRVYYD RTVDQYPFGE AAYAADQTGT SQKQAYTPEE AAQEEESVLW TILISILKLV
     LEILF