ID   CF107_BOVIN             Reviewed;         196 AA.
AC   Q2TA11;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Cilia- and flagella-associated protein 107 {ECO:0000250|UniProtKB:Q8N1D5};
GN   Name=CFAP107 {ECO:0000250|UniProtKB:Q8N1D5};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0007744|PDB:7RRO}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.40 ANGSTROMS), FUNCTION, TISSUE
RP   SPECIFICITY, AND SUBCELLULAR LOCATION.
RX   PubMed=34715025; DOI=10.1016/j.cell.2021.10.007;
RA   Gui M., Farley H., Anujan P., Anderson J.R., Maxwell D.W., Whitchurch J.B.,
RA   Botsch J.J., Qiu T., Meleppattu S., Singh S.K., Zhang Q., Thompson J.,
RA   Lucas J.S., Bingle C.D., Norris D.P., Roy S., Brown A.;
RT   "De novo identification of mammalian ciliary motility proteins using cryo-
RT   EM.";
RL   Cell 184:5791-5806.e19(2021).
CC   -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia axoneme, which is required for
CC       motile cilia beating. {ECO:0000269|PubMed:34715025}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000269|PubMed:34715025}.
CC   -!- TISSUE SPECIFICITY: Expressed in trachea multiciliated cells.
CC       {ECO:0000269|PubMed:34715025}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC111174; AAI11175.1; -; mRNA.
DR   RefSeq; NP_001033296.1; NM_001038207.2.
DR   PDB; 7RRO; EM; 3.40 A; 8/9=1-196.
DR   PDBsum; 7RRO; -.
DR   AlphaFoldDB; Q2TA11; -.
DR   SMR; Q2TA11; -.
DR   STRING; 9913.ENSBTAP00000051842; -.
DR   PaxDb; Q2TA11; -.
DR   Ensembl; ENSBTAT00000055912; ENSBTAP00000051842; ENSBTAG00000012158.
DR   GeneID; 615316; -.
DR   KEGG; bta:615316; -.
DR   CTD; 93190; -.
DR   VEuPathDB; HostDB:ENSBTAG00000012158; -.
DR   VGNC; VGNC:52642; CFAP107.
DR   eggNOG; ENOG502RZRC; Eukaryota.
DR   GeneTree; ENSGT00390000014553; -.
DR   HOGENOM; CLU_100733_1_0_1; -.
DR   InParanoid; Q2TA11; -.
DR   OMA; EKTPQCI; -.
DR   OrthoDB; 1255878at2759; -.
DR   TreeFam; TF328903; -.
DR   Proteomes; UP000009136; Chromosome 16.
DR   Bgee; ENSBTAG00000012158; Expressed in semen and 29 other tissues.
DR   GO; GO:0005879; C:axonemal microtubule; IDA:UniProtKB.
DR   InterPro; IPR037662; CFAP107.
DR   PANTHER; PTHR31180; PTHR31180; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..196
FT                   /note="Cilia- and flagella-associated protein 107"
FT                   /id="PRO_0000247259"
FT   REGION          168..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   196 AA;  23234 MW;  D35059C9E7725B19 CRC64;
     MQFLTAVSPQ SSSTPSWKIE TKYSTRVLTG NWTEERRKFI KATEKTPQTI YRKEYVPFPG
     HRPDQISRWY SKRTVEGLPY KYLITHHQEP SQRYLISTYD DHYNRHNYHP GLPELRTWNR
     HKLLWLPEKA DFPLLGPPTN YGLYEQLKQK WLPPPEATLR ESIYTSSYPR PPAGAMSRRE
     HAIPVPPPRL QPVPHF