ID   CENPM_CHICK             Reviewed;         177 AA.
AC   Q1T7B9;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Centromere protein M;
DE            Short=CENP-M;
GN   Name=CENPM;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION BY MASS SPECTROMETRY, AND
RP   IDENTIFICATION IN A COMPLEX WITH CENPH; CENPI; CENPK; CENPL; CENPO AND
RP   CENPP.
RX   PubMed=16622420; DOI=10.1038/ncb1396;
RA   Okada M., Cheeseman I.M., Hori T., Okawa K., McLeod I.X., Yates J.R. III,
RA   Desai A., Fukagawa T.;
RT   "The CENP-H-I complex is required for the efficient incorporation of newly
RT   synthesized CENP-A into centromeres.";
RL   Nat. Cell Biol. 8:446-457(2006).
CC   -!- FUNCTION: Component of the CENPA-HI complex, a centromeric complex
CC       involved in assembly of kinetochore proteins, mitotic progression and
CC       chromosome segregation. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the CENPA-HI complex, at least composed of CENPH,
CC       CENPI, CENPK, CENPL, CENPM, CENPO and CENPP.
CC       {ECO:0000269|PubMed:16622420}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}. Chromosome, centromere
CC       {ECO:0000305}. Note=Localizes exclusively in the centromeres.
CC       {ECO:0000305}.
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DR   EMBL; AB231849; BAE93414.1; -; mRNA.
DR   RefSeq; NP_001038103.1; NM_001044638.1.
DR   RefSeq; XP_015140565.1; XM_015285079.1.
DR   AlphaFoldDB; Q1T7B9; -.
DR   SMR; Q1T7B9; -.
DR   BioGRID; 679255; 2.
DR   IntAct; Q1T7B9; 1.
DR   STRING; 9031.ENSGALP00000019414; -.
DR   PaxDb; Q1T7B9; -.
DR   Ensembl; ENSGALT00000019440; ENSGALP00000019414; ENSGALG00000011914.
DR   GeneID; 417982; -.
DR   KEGG; gga:417982; -.
DR   CTD; 79019; -.
DR   VEuPathDB; HostDB:geneid_417982; -.
DR   eggNOG; ENOG502S17M; Eukaryota.
DR   GeneTree; ENSGT00390000017504; -.
DR   HOGENOM; CLU_127179_0_0_1; -.
DR   InParanoid; Q1T7B9; -.
DR   OMA; FCELELE; -.
DR   OrthoDB; 1551430at2759; -.
DR   PhylomeDB; Q1T7B9; -.
DR   TreeFam; TF328778; -.
DR   Reactome; R-GGA-141444; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal.
DR   Reactome; R-GGA-2467813; Separation of Sister Chromatids.
DR   Reactome; R-GGA-2500257; Resolution of Sister Chromatid Cohesion.
DR   Reactome; R-GGA-5663220; RHO GTPases Activate Formins.
DR   Reactome; R-GGA-9648025; EML4 and NUDC in mitotic spindle formation.
DR   PRO; PR:Q1T7B9; -.
DR   Proteomes; UP000000539; Chromosome 1.
DR   Bgee; ENSGALG00000011914; Expressed in testis and 9 other tissues.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR020987; Centromere_Cenp-M.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR34436; PTHR34436; 1.
DR   Pfam; PF11111; CENP-M; 1.
PE   1: Evidence at protein level;
KW   Centromere; Chromosome; Nucleus; Reference proteome.
FT   CHAIN           1..177
FT                   /note="Centromere protein M"
FT                   /id="PRO_0000249490"
SQ   SEQUENCE   177 AA;  19625 MW;  577DFD82451816C1 CRC64;
     MAVLRPFDKL PELNSATILL VGAEGGPQQQ LAEAMLREKK DFNINIHLAS SLPLPSERDH
     LRPRIDLIAF VIDIKSKYSL KNVQASLAYV DVRFFLGKVC FLVTGVGRAN NCSVEMNAIW
     KLGEDYCSPV IFCELELEGI RVATAQRLLR MLQICAGRVP GVSALYFSLL MRNSAGD