YSL8_ORYSJ
ID YSL8_ORYSJ Reviewed; 694 AA.
AC Q0E4J6; A0A0N7KEK3; Q25CH8; Q6ZGM6;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Probable metal-nicotianamine transporter YSL8;
DE AltName: Full=Protein YELLOW STRIPE LIKE 8;
DE Short=OsYSL8;
GN Name=YSL8; OrderedLocusNames=Os02g0116400, LOC_Os02g02460;
GN ORFNames=OJ1442_E05.17, OsJ_004979;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=15255870; DOI=10.1111/j.1365-313x.2004.02146.x;
RA Koike S., Inoue H., Mizuno D., Takahashi M., Nakanishi H., Mori S.,
RA Nishizawa N.K.;
RT "OsYSL2 is a rice metal-nicotianamine transporter that is regulated by iron
RT and expressed in the phloem.";
RL Plant J. 39:415-424(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP TISSUE SPECIFICITY.
RX PubMed=19049971; DOI=10.1074/jbc.m806042200;
RA Inoue H., Kobayashi T., Nozoye T., Takahashi M., Kakei Y., Suzuki K.,
RA Nakazono M., Nakanishi H., Mori S., Nishizawa N.K.;
RT "Rice OsYSL15 is an iron-regulated iron(III)-deoxymugineic acid Transporter
RT expressed in the roots and is essential for iron uptake in early growth of
RT the seedlings.";
RL J. Biol. Chem. 284:3470-3479(2009).
CC -!- FUNCTION: May be involved in the transport of nicotianamine-chelated
CC metals. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in root epidermis and exoderm.
CC {ECO:0000269|PubMed:19049971}.
CC -!- SIMILARITY: Belongs to the YSL (TC 2.A.67.2) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD07718.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=EAZ21496.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AB190918; BAE91888.1; -; mRNA.
DR EMBL; AP004121; BAD07718.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP008208; BAF07592.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS76657.1; -; Genomic_DNA.
DR EMBL; CM000139; EAZ21496.1; ALT_INIT; Genomic_DNA.
DR RefSeq; XP_015626364.1; XM_015770878.1.
DR AlphaFoldDB; Q0E4J6; -.
DR STRING; 4530.OS02T0116400-01; -.
DR PaxDb; Q0E4J6; -.
DR PRIDE; Q0E4J6; -.
DR EnsemblPlants; Os02t0116400-01; Os02t0116400-01; Os02g0116400.
DR Gramene; Os02t0116400-01; Os02t0116400-01; Os02g0116400.
DR KEGG; osa:4328078; -.
DR eggNOG; ENOG502QQ2H; Eukaryota.
DR HOGENOM; CLU_015477_2_0_1; -.
DR InParanoid; Q0E4J6; -.
DR OMA; IMIISYK; -.
DR OrthoDB; 525938at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q0E4J6; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR PANTHER; PTHR31645; PTHR31645; 1.
DR Pfam; PF03169; OPT; 1.
DR TIGRFAMs; TIGR00728; OPT_sfam; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..694
FT /note="Probable metal-nicotianamine transporter YSL8"
FT /id="PRO_0000363871"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 215..235
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 319..339
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 506..526
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 567..587
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 608..628
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 643..663
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 281
FT /note="I -> V (in Ref. 1; BAE91888)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 694 AA; 75633 MW; 3817B84B317A040C CRC64;
MMAAAAGEGE AEVTREVISV STEKAFEGKA LPAWSEQITV RSLVVSAVLG TFLSFIVMKL
NLTSGIVPSL NVSAGLLAFF LMKTWTSALE RCGVFPKPFT RQENTVVQTC VISCSSIAFS
GGFGTYILGM SKKIAEGFDE AEAKTSINVE EPSLGRLIAF LFLVSFVGLF SIVPLRKIMI
ISYKLTYPSG SATAHLINSF HTPQGAIQAK HQVSILFKSF VGSFLWSLFQ WFYAAGPGCG
FSSFPTFGMV AYSRRFYFDF SATYVGVGMI CPYIINFSLL IGSVVSWGIM WPYIESKKGS
WYDAGLPKSS LHGLNGYQVF ISIAMIVGDG LFNFFSIVLR TAYDLYLKRR GGASKQPQET
PFAGATGTER QVLSFDDRRR TQVFLKDQIP TTIAAAAYVL LAAISVVAIP HIFRQLRPKH
VVWAYVVAPL FAFCNAYGTG LTDWSLSSSY GKLAIFIFGA NIGAKDGGVV AGLAACGLMM
GIVSTASDLV QDFKTGYLTL TSPRSMFVSQ VLGTGMGCII SPMVFWMFYK ANNIGMEEGF
PAPYAKIYRG IALLGVNGWD QLPRYCLRFC LAFFLLAIAI CALKEVAKQR GWWIQDFIPS
ALGMAVPFFL GSFFTIDMCV GSLVLFLWSR SDPVRAHTFA PAVASGLICG DGIWSLPSSI
LSLANVNPPM CMRVFSTATN DKVQLFLRTL PTPP
