ID   YOPN_YEREN              Reviewed;         293 AA.
AC   P16945;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Outer membrane protein YopN;
DE   AltName: Full=LcrE;
DE   AltName: Full=Yop4b;
GN   Name=yopN; Synonyms=lcrE;
OS   Yersinia enterocolitica.
OG   Plasmid pYV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype O:3;
RX   PubMed=2160939; DOI=10.1128/jb.172.6.3152-3162.1990;
RA   Viitanen A.-M., Toivanen P., Skurnik M.;
RT   "The lcrE gene is part of an operon in the lcr region of Yersinia
RT   enterocolitica O:3.";
RL   J. Bacteriol. 172:3152-3162(1990).
CC   -!- FUNCTION: Plays a major role in regulation of the low-calcium response.
CC       Seems to sense the calcium concentration and to transmit a signal to
CC       shut off yop transcription when the calcium concentration is high.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane.
CC   -!- INDUCTION: Temperature seems to play the major role in regulation of
CC       transcription of the yopN-containing operon of pYV, whereas Ca(2+)
CC       concentration has only a moderate effect at 37 degrees C., and no
CC       effect at room temperature.
CC   -!- SIMILARITY: Belongs to the HrpJ/YopN family. {ECO:0000305}.
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DR   EMBL; M32097; AAA98429.1; -; Genomic_DNA.
DR   PIR; A35392; A35392.
DR   RefSeq; WP_014609482.1; NZ_CWIX01000081.1.
DR   AlphaFoldDB; P16945; -.
DR   SMR; P16945; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009986; C:cell surface; IEA:InterPro.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IEA:InterPro.
DR   GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR   InterPro; IPR010812; HrpJ-like.
DR   InterPro; IPR013401; T3SS_LcrE.
DR   Pfam; PF07201; HrpJ; 1.
DR   TIGRFAMs; TIGR02568; LcrE; 1.
PE   2: Evidence at transcript level;
KW   Calcium; Cell outer membrane; Membrane; Plasmid; Virulence.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..293
FT                   /note="Outer membrane protein YopN"
FT                   /id="PRO_0000066370"
SQ   SEQUENCE   293 AA;  32924 MW;  C0BAB9F14F265CCF CRC64;
     MTTLHNLSYG NTPLRNEHPE IASSQIVNQT LGQFRGESVQ IVSGTLQSIA DMAEEVTFVF
     SERKELSLDK RKLSDSQARV SDVEEQVNQY LSKVPELKQK QNVSELLSLL SNSPNISLSQ
     LKAYLEGKSE EPSEQFKMLC GLRDALKGRP ELAHLLHLVE QALVSMVEEQ EEAIVLGARI
     TPEAYRESQS GVNPLQPLRD TYRDAVMGYQ GINAIWSDLQ KRFPNGDIDS VILFLQKALS
     ADLQSQQSGS EREKLEIVIS DLQKLKEFRS VSDQVKGFWQ LFSEGITNGL RPF