ID   YOPC_BACSU              Reviewed;         442 AA.
AC   O31935;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Putative toxin YopC {ECO:0000305};
DE   AltName: Full=SPbeta prophage-derived protein YopC;
GN   Name=yopC; OrderedLocusNames=BSU20940;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: May be the toxic component of a type II toxin-antitoxin (TA)
CC       system. Neutralized by its cognate antitoxin YopB.
CC       {ECO:0000250|UniProtKB:P9WLP9}.
CC   -!- SUBUNIT: Forms a complex with cognate antitoxin YopB.
CC       {ECO:0000250|UniProtKB:P9WLP9}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the MbcT/ParT/Res
CC       family. {ECO:0000305}.
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DR   EMBL; AL009126; CAB14012.1; -; Genomic_DNA.
DR   RefSeq; NP_389977.1; NC_000964.3.
DR   RefSeq; WP_004399370.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O31935; -.
DR   SMR; O31935; -.
DR   STRING; 224308.BSU20940; -.
DR   PaxDb; O31935; -.
DR   PRIDE; O31935; -.
DR   EnsemblBacteria; CAB14012; CAB14012; BSU_20940.
DR   GeneID; 939177; -.
DR   KEGG; bsu:BSU20940; -.
DR   PATRIC; fig|224308.179.peg.2286; -.
DR   eggNOG; ENOG5032TMW; Bacteria.
DR   OMA; VECYLEL; -.
DR   BioCyc; BSUB:BSU20940-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   InterPro; IPR014914; RES_dom.
DR   Pfam; PF08808; RES; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..442
FT                   /note="Putative toxin YopC"
FT                   /id="PRO_0000360461"
SQ   SEQUENCE   442 AA;  52149 MW;  E3C23B24888B8A52 CRC64;
     MDLYRKAKRL KKELSKHEEI NDSLKELAFD IFKELTVKPE FIDKNTNDVI GEEKINTSTF
     SNKERLDILI EWTIEIDPIL SFIIDKCDIP IERTGGDDLD AFMENVYTEY IEELHKLPNR
     KSFDSSKITK IESFAQQITK TIELYLDGYV HLAYAEFDKG MNIFSEEVNI EELLLYNIDS
     IRIPCKFFRM RTSNTEVFSK DDMFHIPFEK RGIIRTNRFS IPGFPCLYLG SSSLVCWEEL
     GRPDLNTTYT SVFHLEDEDI KILDLSVSPT ELADNLKKFF EITFRRKIYK FNAYFMTWIL
     ISACLIRVKK QKDIFKPEYI IPQFLLEWVK QTESSEYWGI CYLSSKINRQ TIENYKLYKN
     YAIPVRQRKD SGHCSLLGET FQISDPVAWE TFQSHKDSPE SLPIKNPLFP ETEGTHHDYH
     KTELGRLEAF LIRYRSVVKD QL