ID   YOP1_MAGO7              Reviewed;         170 AA.
AC   Q51VY4; A4R4S4; G4NGX4;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 2.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Protein YOP1;
GN   Name=YOP1; ORFNames=MGG_12127;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Required to generate and maintain the structure of the
CC       tubular endoplasmic reticulum network and the vacuole. Induces high
CC       curvature in membranes and causes membrane tubule formation. Involved
CC       in membrane/vesicle trafficking. {ECO:0000250|UniProtKB:Q12402}.
CC   -!- SUBUNIT: Oligomer. {ECO:0000250|UniProtKB:Q12402}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:Q12402}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q12402}. Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q12402}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- DOMAIN: The short lumenal loops between transmembrane domains 1 and 2
CC       and between transmembrane domains 3 and 4 may impart a wedge-like
CC       configuration, thus deforming membranes.
CC       {ECO:0000250|UniProtKB:Q12402}.
CC   -!- SIMILARITY: Belongs to the DP1 family. {ECO:0000305}.
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DR   EMBL; CM001236; EHA47484.1; -; Genomic_DNA.
DR   RefSeq; XP_003719851.1; XM_003719803.1.
DR   AlphaFoldDB; Q51VY4; -.
DR   STRING; 318829.MGG_12127T0; -.
DR   PRIDE; Q51VY4; -.
DR   EnsemblFungi; MGG_12127T0; MGG_12127T0; MGG_12127.
DR   GeneID; 5049887; -.
DR   KEGG; mgr:MGG_12127; -.
DR   VEuPathDB; FungiDB:MGG_12127; -.
DR   eggNOG; KOG1725; Eukaryota.
DR   HOGENOM; CLU_028431_2_1_1; -.
DR   InParanoid; Q51VY4; -.
DR   OMA; FILVLWM; -.
DR   OrthoDB; 1473891at2759; -.
DR   Proteomes; UP000009058; Chromosome 6.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR004345; TB2_DP1_HVA22.
DR   PANTHER; PTHR12300; PTHR12300; 1.
DR   Pfam; PF03134; TB2_DP1_HVA22; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Golgi apparatus; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..170
FT                   /note="Protein YOP1"
FT                   /id="PRO_0000101854"
FT   TOPO_DOM        1..35
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
FT   TRANSMEM        36..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
FT   TOPO_DOM        56
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
FT   TRANSMEM        57..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
FT   TOPO_DOM        77..86
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
FT   TRANSMEM        87..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
FT   TOPO_DOM        104..105
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
FT   TRANSMEM        106..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
FT   TOPO_DOM        125..170
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q12402"
SQ   SEQUENCE   170 AA;  19327 MW;  45907B2FCA60953E CRC64;
     MSSPQDRAQY YIGQLDRELS KYPALNNLER TTGVPKAYAV VGVVVLYFFL IVFNLGGQLL
     TNIAGFGIPA YYSLDALFSA NKEDDTQWLT YWVVFAMFTV VESLVSVVYW FPFYYMFKFV
     FLLWLSLPAF KGADIIFRSF LAPTLSRYFV HSRPASSNLR AKADSAGKAE