YNDE_BACSU
ID YNDE_BACSU Reviewed; 363 AA.
AC O31809;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Spore germination protein YndE;
GN Name=yndE; OrderedLocusNames=BSU17760;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [2]
RP FUNCTION IN GERMINATION.
RX PubMed=10762253; DOI=10.1128/jb.182.9.2513-2519.2000;
RA Paidhungat M., Setlow P.;
RT "Role of ger proteins in nutrient and nonnutrient triggering of spore
RT germination in Bacillus subtilis.";
RL J. Bacteriol. 182:2513-2519(2000).
CC -!- FUNCTION: Involved in the germinative response to L-alanine. Could be
CC an amino acid transporter (By similarity). {ECO:0000250,
CC ECO:0000269|PubMed:10762253}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
CC {ECO:0000305}.
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DR EMBL; AL009126; CAB13660.1; -; Genomic_DNA.
DR PIR; E69889; E69889.
DR RefSeq; NP_389659.1; NC_000964.3.
DR RefSeq; WP_003231622.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; O31809; -.
DR SMR; O31809; -.
DR STRING; 224308.BSU17760; -.
DR TCDB; 2.A.3.9.4; the amino acid-polyamine-organocation (apc) family.
DR PaxDb; O31809; -.
DR PRIDE; O31809; -.
DR EnsemblBacteria; CAB13660; CAB13660; BSU_17760.
DR GeneID; 936538; -.
DR KEGG; bsu:BSU17760; -.
DR PATRIC; fig|224308.179.peg.1936; -.
DR eggNOG; COG0531; Bacteria.
DR InParanoid; O31809; -.
DR OMA; FIFVSAP; -.
DR PhylomeDB; O31809; -.
DR BioCyc; BSUB:BSU17760-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0009847; P:spore germination; IEA:InterPro.
DR InterPro; IPR004761; Spore_GerAB.
DR PANTHER; PTHR34975; PTHR34975; 1.
DR Pfam; PF03845; Spore_permease; 1.
DR TIGRFAMs; TIGR00912; 2A0309; 1.
PE 1: Evidence at protein level;
KW Amino-acid transport; Cell membrane; Germination; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..363
FT /note="Spore germination protein YndE"
FT /id="PRO_0000360156"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 363 AA; 40471 MW; 1F69D5E3EF312EB5 CRC64;
MFSPTSKITT AQATIIIINY MLAAGVLTLP RTVTEQTQSP DGWISVLLGG VLAVIAGMII
AKLSQQYPKE TFYEYSRHIV GKWLGHLISI VFITYFLALG AFEVRVMSEI VDFFLLEGTP
SWAIIMTVLW IGLYSITQGL DPIARLFEMI FPITVIIFLT IALMSLGIFE INNLRPVLGD
GIMPVLRGVK TTNLSFTCSE IMFILVAFMK KPKNAVKAVV IGTGVVTSFY MITMIMVIGA
LSVEGVVTRT WPGLDLMRSF EIPGLIFERF ESFLLVIWIM QLFATFIITF YAASLGVSQV
FKKKPLSCMF GLLPVIYILS CMPKNENDVF ILGDTVSHIA LYIFGALPIL LLVISKWRKR
GEK
