YNCE_ECOLI
ID YNCE_ECOLI Reviewed; 353 AA.
AC P76116; Q2MBB1;
DT 21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=Uncharacterized protein YncE;
DE Flags: Precursor;
GN Name=yncE; OrderedLocusNames=b1452, JW1447;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP INDUCTION.
RX PubMed=12746439; DOI=10.1074/jbc.m303381200;
RA McHugh J.P., Rodriguez-Quinones F., Abdul-Tehrani H., Svistunenko D.A.,
RA Poole R.K., Cooper C.E., Andrews S.C.;
RT "Global iron-dependent gene regulation in Escherichia coli. A new mechanism
RT for iron homeostasis.";
RL J. Biol. Chem. 278:29478-29486(2003).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBSTRATE FOR SECB.
RC STRAIN=K12 / MC4100;
RX PubMed=16352602; DOI=10.1074/jbc.m509929200;
RA Baars L., Ytterberg A.J., Drew D., Wagner S., Thilo C., van Wijk K.J.,
RA de Gier J.W.;
RT "Defining the role of the Escherichia coli chaperone SecB using comparative
RT proteomics.";
RL J. Biol. Chem. 281:10024-10034(2006).
RN [5]
RP PRELIMINARY CRYSTALLIZATION, AND SUBUNIT.
RX PubMed=18931447; DOI=10.1107/s1744309108029515;
RA Baba-Dikwa A., Thompson D., Spencer N.J., Andrews S.C., Watson K.A.;
RT "Overproduction, purification and preliminary X-ray diffraction analysis of
RT YncE, an iron-regulated Sec-dependent periplasmic protein from Escherichia
RT coli.";
RL Acta Crystallogr. F 64:966-969(2008).
CC -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:18931447}.
CC -!- INDUCTION: Repressed by Fur. {ECO:0000269|PubMed:12746439}.
CC -!- MISCELLANEOUS: Preliminary crystallization indicates the presence of a
CC single beta-propeller domain that contains 7 4-stranded beta-sheets.
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DR EMBL; U00096; AAC74534.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76445.1; -; Genomic_DNA.
DR PIR; G64897; G64897.
DR RefSeq; NP_415969.1; NC_000913.3.
DR RefSeq; WP_000550695.1; NZ_SSZK01000021.1.
DR PDB; 3VGZ; X-ray; 1.70 A; A/B/C/D=1-353.
DR PDB; 3VH0; X-ray; 2.90 A; A/B/C/D=1-353.
DR PDBsum; 3VGZ; -.
DR PDBsum; 3VH0; -.
DR AlphaFoldDB; P76116; -.
DR SMR; P76116; -.
DR BioGRID; 4260198; 8.
DR DIP; DIP-28079N; -.
DR IntAct; P76116; 4.
DR STRING; 511145.b1452; -.
DR jPOST; P76116; -.
DR PaxDb; P76116; -.
DR PRIDE; P76116; -.
DR EnsemblBacteria; AAC74534; AAC74534; b1452.
DR EnsemblBacteria; BAE76445; BAE76445; BAE76445.
DR GeneID; 946006; -.
DR KEGG; ecj:JW1447; -.
DR KEGG; eco:b1452; -.
DR PATRIC; fig|1411691.4.peg.816; -.
DR EchoBASE; EB3537; -.
DR eggNOG; COG3391; Bacteria.
DR HOGENOM; CLU_056358_1_0_6; -.
DR InParanoid; P76116; -.
DR OMA; QDDGKEH; -.
DR PhylomeDB; P76116; -.
DR BioCyc; EcoCyc:G6763-MON; -.
DR PRO; PR:P76116; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003677; F:DNA binding; IDA:EcoCyc.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR011048; Haem_d1_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR SUPFAM; SSF51004; SSF51004; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Signal.
FT SIGNAL 1..30
FT /evidence="ECO:0000255"
FT CHAIN 31..353
FT /note="Uncharacterized protein YncE"
FT /id="PRO_0000013838"
FT STRAND 34..49
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 50..53
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 54..59
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 63..65
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 66..74
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 76..78
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 81..89
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 93..97
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 98..101
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 102..107
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 108..111
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 112..117
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 118..120
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 123..129
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 142..149
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 150..153
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 154..163
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 165..170
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 171..174
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 175..180
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 191..193
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 194..197
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 198..202
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 206..212
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 213..216
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 217..223
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 227..229
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 233..239
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 240..243
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 244..259
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 260..262
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 265..270
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 277..280
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 281..284
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 285..290
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 291..294
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 295..300
FT /evidence="ECO:0007829|PDB:3VGZ"
FT TURN 301..304
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 305..311
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 314..321
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 327..333
FT /evidence="ECO:0007829|PDB:3VGZ"
FT STRAND 338..340
FT /evidence="ECO:0007829|PDB:3VH0"
FT STRAND 346..352
FT /evidence="ECO:0007829|PDB:3VGZ"
SQ SEQUENCE 353 AA; 38613 MW; F0CA76C737035671 CRC64;
MHLRHLFSSR LRGSLLLGSL LVVSSFSTQA AEEMLRKAVG KGAYEMAYSQ QENALWLATS
QSRKLDKGGV VYRLDPVTLE VTQAIHNDLK PFGATINNTT QTLWFGNTVN SAVTAIDAKT
GEVKGRLVLD DRKRTEEVRP LQPRELVADD ATNTVYISGI GKESVIWVVD GGNIKLKTAI
QNTGKMSTGL ALDSEGKRLY TTNADGELIT IDTADNKILS RKKLLDDGKE HFFINISLDT
ARQRAFITDS KAAEVLVVDT RNGNILAKVA APESLAVLFN PARNEAYVTH RQAGKVSVID
AKSYKVVKTF DTPTHPNSLA LSADGKTLYV SVKQKSTKQQ EATQPDDVIR IAL
