YFG5_SCHPO
ID YFG5_SCHPO Reviewed; 291 AA.
AC O13844;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Uncharacterized mitochondrial carrier C19G12.05;
GN ORFNames=SPAC19G12.05;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAB10116.1; -; Genomic_DNA.
DR PIR; T37992; T37992.
DR RefSeq; NP_594420.1; NM_001019849.2.
DR AlphaFoldDB; O13844; -.
DR SMR; O13844; -.
DR BioGRID; 278917; 3.
DR STRING; 4896.SPAC19G12.05.1; -.
DR SwissPalm; O13844; -.
DR MaxQB; O13844; -.
DR PaxDb; O13844; -.
DR EnsemblFungi; SPAC19G12.05.1; SPAC19G12.05.1:pep; SPAC19G12.05.
DR GeneID; 2542456; -.
DR KEGG; spo:SPAC19G12.05; -.
DR PomBase; SPAC19G12.05; -.
DR VEuPathDB; FungiDB:SPAC19G12.05; -.
DR eggNOG; KOG0756; Eukaryota.
DR HOGENOM; CLU_015166_5_1_1; -.
DR InParanoid; O13844; -.
DR OMA; CPAFIVG; -.
DR PhylomeDB; O13844; -.
DR Reactome; R-SPO-70263; Gluconeogenesis.
DR Reactome; R-SPO-75105; Fatty acyl-CoA biosynthesis.
DR PRO; PR:O13844; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; ISS:PomBase.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0071913; F:citrate secondary active transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005371; F:tricarboxylate secondary active transmembrane transporter activity; ISS:PomBase.
DR GO; GO:0006843; P:mitochondrial citrate transmembrane transport; ISO:PomBase.
DR Gene3D; 1.50.40.10; -; 2.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..291
FT /note="Uncharacterized mitochondrial carrier C19G12.05"
FT /id="PRO_0000311180"
FT TRANSMEM 21..41
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 108..128
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 259..280
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 15..93
FT /note="Solcar 1"
FT REPEAT 104..190
FT /note="Solcar 2"
FT REPEAT 201..287
FT /note="Solcar 3"
SQ SEQUENCE 291 AA; 31574 MW; DE12CA5D622E87EA CRC64;
MSTVAKTNPK SSNKPGPVKS IIAGGVAGAI EISITYPAEF AKTRLQLYRN VEGTKAKLPP
FGLEWYRGCS TVIVGNSLKA AVRFFAFDSI KKSLSDEHGH LTGPRTVLAG LGAGVAESVL
VLTPFESIKT AIIDDRKRPN PRLKGFLQAS RIIVHENGIR GLYRGLAATV ARQAANSGVR
FTAYNSIKQS LQSRLPPDEK LSTVTTFLVG SVAGIITVYC TQPIDTVKSR MQSLSASKEY
KNSIHCAYKI LTQDGLLRFW SGATPRLARL ILSGGIVFTV YEKVMEILKP F
