ID   YFEO_SALTY              Reviewed;         411 AA.
AC   Q93IM6;
DT   11-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Putative ion-transport protein YfeO;
GN   Name=yfeO; OrderedLocusNames=STM2404;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=C52;
RA   Norel F.;
RT   "Nucleotide sequence of the Salmonella typhimurium ipd gene encoding a
RT   putative indole-3-pyruvate decarboxylase.";
RL   Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC       {ECO:0000305}.
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DR   EMBL; AJ401270; CAC48240.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL21304.1; -; Genomic_DNA.
DR   RefSeq; NP_461345.1; NC_003197.2.
DR   RefSeq; WP_000468920.1; NC_003197.2.
DR   AlphaFoldDB; Q93IM6; -.
DR   SMR; Q93IM6; -.
DR   STRING; 99287.STM2404; -.
DR   PaxDb; Q93IM6; -.
DR   EnsemblBacteria; AAL21304; AAL21304; STM2404.
DR   GeneID; 1253926; -.
DR   KEGG; stm:STM2404; -.
DR   PATRIC; fig|99287.12.peg.2546; -.
DR   HOGENOM; CLU_053130_0_0_6; -.
DR   OMA; WKVPGHA; -.
DR   PhylomeDB; Q93IM6; -.
DR   BioCyc; SENT99287:STM2404-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   HAMAP; MF_01115; CLC_YfeO; 1.
DR   InterPro; IPR022969; Chloride_channel_YfeO.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF81340; SSF81340; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion channel; Ion transport; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..411
FT                   /note="Putative ion-transport protein YfeO"
FT                   /id="PRO_0000094498"
FT   TRANSMEM        9..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        223..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        258..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        295..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        322..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        345..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        376..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   411 AA;  42984 MW;  463C3197F43DB645 CRC64;
     MFHPRARTML LLSLPALIIG VASSLVLIAA MKVASVFQQF LWQRLPTSIG IAYDSPFWIV
     GMLTLTGIVV GLIIRYSPGH AGPDPAIEPL ISMPVSPSAL PGLLLALIIG LAGGVSLGPE
     HPIMTINIAL AAAFGSRLFP RITALDWTIL ASAGTIGALF GTPVAAALIF SQTLSGSNDI
     PMWDRLFAPL MAAAAGSLTT SLFFHPHFSL PIAHYTQMRL VDIASGAIVA AIAIAAGMVA
     VWCLPRLHEL LHRLKNPVLI LGIGGFILGI LGVIGGPLTL FKGLDEMQQM AFSQTLGAGD
     YFTLAVVKLA ALVIAAASGF RGGRIFPAVF IGAALGLMLH AHVEAVPAAI TVSCAILGLV
     LVVTRDGWLS LFMAAVVVPD TNLLPLLCIV MLPAWLLLAG KPLLAANRHE P