YFEC_YERPE
ID YFEC_YERPE Reviewed; 294 AA.
AC Q56954; Q0WE83;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 145.
DE RecName: Full=Chelated iron transport system membrane protein YfeC;
GN Name=yfeC; OrderedLocusNames=YPO2441, y1895, YP_2229;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM6;
RX PubMed=9495751; DOI=10.1128/jb.180.5.1135-1147.1998;
RA Bearden S.W., Staggs T.M., Perry R.D.;
RT "An ABC transporter system of Yersinia pestis allows utilization of
RT chelated iron by Escherichia coli SAB11.";
RL J. Bacteriol. 180:1135-1147(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Part of an ATP-driven transport system YfeABC for chelated
CC iron.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC-3 integral membrane protein family.
CC {ECO:0000305}.
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DR EMBL; U50597; AAC46149.1; -; Genomic_DNA.
DR EMBL; AL590842; CAL21069.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM85462.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS62435.1; -; Genomic_DNA.
DR PIR; AB0298; AB0298.
DR RefSeq; WP_002211844.1; NZ_WUCM01000025.1.
DR RefSeq; YP_002347405.1; NC_003143.1.
DR AlphaFoldDB; Q56954; -.
DR SMR; Q56954; -.
DR IntAct; Q56954; 1.
DR STRING; 214092.YPO2441; -.
DR TCDB; 3.A.1.15.4; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q56954; -.
DR DNASU; 1146842; -.
DR EnsemblBacteria; AAM85462; AAM85462; y1895.
DR EnsemblBacteria; AAS62435; AAS62435; YP_2229.
DR GeneID; 57976238; -.
DR KEGG; ype:YPO2441; -.
DR KEGG; ypk:y1895; -.
DR KEGG; ypm:YP_2229; -.
DR PATRIC; fig|214092.21.peg.2852; -.
DR eggNOG; COG1108; Bacteria.
DR HOGENOM; CLU_028808_4_0_6; -.
DR OMA; GAWLSYY; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0071281; P:cellular response to iron ion; EXP:CollecTF.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR GO; GO:0010043; P:response to zinc ion; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.3470.10; -; 1.
DR InterPro; IPR037294; ABC_BtuC-like.
DR InterPro; IPR001626; ABC_TroCD.
DR PANTHER; PTHR30477; PTHR30477; 1.
DR Pfam; PF00950; ABC-3; 1.
DR SUPFAM; SSF81345; SSF81345; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Iron; Iron transport;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..294
FT /note="Chelated iron transport system membrane protein
FT YfeC"
FT /id="PRO_0000171156"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 194..214
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 294 AA; 31807 MW; B6B644AD3AE72F5E CRC64;
MLELLLQPFN YNYMVKAIWV SAIVGAVCAF LSAYLMLKGW SLMGDALSHS VVPGVAGAYA
LGFPYAAGAF FTGMLAALAM TLVRHITRLR EDAIIGFIFS TFFAVGLLIV SLNPTSVNVQ
SIIFGNILGI ADEDVLQVEI IILVSFVILC LIWKDLLAVF FDESHAMSIG LSPLRLKILF
FTLLSACTVA ALQTVGAILV IAMVVTPGAT AYLLTDRFGR LLIIAIAIGA ITSAFGAYLS
FYLDGATGGV IVTLQTLVFL PAFFFAPKHG LLATRYRTRL KRRHPPVHLP EDNL
