YE85_SCHPO
ID YE85_SCHPO Reviewed; 595 AA.
AC O14301;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Uncharacterized WD repeat-containing protein C9G1.05;
GN ORFNames=SPAC9G1.05;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SIMILARITY: Belongs to the WD repeat AIP1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAB11489.1; -; Genomic_DNA.
DR PIR; T39228; T39228.
DR RefSeq; NP_593560.1; NM_001018993.2.
DR AlphaFoldDB; O14301; -.
DR SMR; O14301; -.
DR BioGRID; 279243; 29.
DR IntAct; O14301; 1.
DR STRING; 4896.SPAC9G1.05.1; -.
DR iPTMnet; O14301; -.
DR MaxQB; O14301; -.
DR PaxDb; O14301; -.
DR PRIDE; O14301; -.
DR EnsemblFungi; SPAC9G1.05.1; SPAC9G1.05.1:pep; SPAC9G1.05.
DR GeneID; 2542795; -.
DR KEGG; spo:SPAC9G1.05; -.
DR PomBase; SPAC9G1.05; -.
DR VEuPathDB; FungiDB:SPAC9G1.05; -.
DR eggNOG; KOG0318; Eukaryota.
DR HOGENOM; CLU_015246_1_0_1; -.
DR InParanoid; O14301; -.
DR OMA; TNPAKHT; -.
DR PhylomeDB; O14301; -.
DR Reactome; R-SPO-114608; Platelet degranulation.
DR PRO; PR:O14301; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0030479; C:actin cortical patch; ISO:PomBase.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0051286; C:cell tip; HDA:PomBase.
DR GO; GO:0030864; C:cortical actin cytoskeleton; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0030042; P:actin filament depolymerization; IBA:GO_Central.
DR GO; GO:0030836; P:positive regulation of actin filament depolymerization; IBA:GO_Central.
DR GO; GO:1903920; P:positive regulation of actin filament severing; IDA:PomBase.
DR Gene3D; 2.130.10.10; -; 2.
DR InterPro; IPR024977; Apc4_WD40_dom.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF13360; PQQ_2; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00320; WD40; 10.
DR SUPFAM; SSF50978; SSF50978; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..595
FT /note="Uncharacterized WD repeat-containing protein
FT C9G1.05"
FT /id="PRO_0000051495"
FT REPEAT 56..95
FT /note="WD 1"
FT REPEAT 100..143
FT /note="WD 2"
FT REPEAT 144..184
FT /note="WD 3"
FT REPEAT 187..226
FT /note="WD 4"
FT REPEAT 229..268
FT /note="WD 5"
FT REPEAT 313..352
FT /note="WD 6"
FT REPEAT 356..393
FT /note="WD 7"
FT REPEAT 433..472
FT /note="WD 8"
FT REPEAT 477..516
FT /note="WD 9"
FT REPEAT 520..559
FT /note="WD 10"
FT REPEAT 564..594
FT /note="WD 11"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 595 AA; 65266 MW; 4F9B4FAF32823ECE CRC64;
MSSQLKSTWA PVPSTKPSQP CKIGTDFKGE RIVYPANKAI IIREIEKQEN CFQYNEHTAP
TTVARFSPSG YYVASGDNQG NVRIWDCAGE DKILKNQVTA ISGRITDLDW DGDSQRIIAV
GEGKERYGHA FTADSGNSVG EIFGHSSVVN AVSLRKSRPF RAATASDDNS INFFHGTPYR
FNRSLRVHSK FVYDVRYSPN DERFASAGAD GKVYVFDGKT GDQVYEIDAH KGSIFSISWS
PDSSQFVTSS AGYSCKIWDA NTGSLIREWL SSDKKQLVGT VWPTKDLIIV VNSKGNLTYL
NPSDCKVIDT IYGHQRSITA ATLSPDATHF YTASYDGTVL SWDIGKQKAF PLVGESHTNQ
VMQMIMADDH VITIGMDDTL RVIDIKQGCF AKDNVFPTGY QPIGVCSVED CLILVTVSDI
QVLRSLTGVS TAKTIYQPSA VASHPLKSEF CVGGEDCCVY IHTLEKGELC EVAQCKDSTA
PITCLAYSPD GKYLACGDAS GKVVLYDANS REVITSRWAF HTGRILGMSW NAKSTHLATA
SLDTNIHIYS VERPMKYIAM KNAHSLGATQ VEWVSENELL STGSDAAIKV WSVTF
