ID   CATC_RHOOP              Reviewed;          93 AA.
AC   P95609;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Muconolactone Delta-isomerase;
DE            Short=MIase;
DE            EC=5.3.3.4 {ECO:0000250|UniProtKB:P00948};
GN   Name=catC;
OS   Rhodococcus opacus (Nocardia opaca).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Rhodococcus.
OX   NCBI_TaxID=37919;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 2-21.
RC   STRAIN=1CP;
RX   PubMed=8990288; DOI=10.1128/jb.179.2.370-381.1997;
RA   Eulberg D., Golovleva L.A., Schloemann M.;
RT   "Characterization of catechol catabolic genes from Rhodococcus erythropolis
RT   1CP.";
RL   J. Bacteriol. 179:370-381(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate;
CC         Xref=Rhea:RHEA:12348, ChEBI:CHEBI:58425, ChEBI:CHEBI:58736;
CC         EC=5.3.3.4; Evidence={ECO:0000250|UniProtKB:P00948};
CC   -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-
CC       4,5-dihydro-2-furylacetate from catechol: step 3/3.
CC   -!- SUBUNIT: Homodecamer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the muconolactone Delta-isomerase family.
CC       {ECO:0000305}.
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DR   EMBL; X99622; CAA67935.1; -; Genomic_DNA.
DR   RefSeq; WP_005573881.1; NZ_NWMZ01000001.1.
DR   AlphaFoldDB; P95609; -.
DR   SMR; P95609; -.
DR   STRING; 37919.EP51_30995; -.
DR   GeneID; 66788845; -.
DR   eggNOG; COG4829; Bacteria.
DR   UniPathway; UPA00157; UER00260.
DR   GO; GO:0016159; F:muconolactone delta-isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR026029; MLI_dom.
DR   InterPro; IPR003464; Muconolactone_d_Isoase.
DR   Pfam; PF02426; MIase; 1.
DR   PIRSF; PIRSF001486; CatC; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   TIGRFAMs; TIGR03221; muco_delta; 1.
PE   1: Evidence at protein level;
KW   Aromatic hydrocarbons catabolism; Direct protein sequencing; Isomerase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:8990288"
FT   CHAIN           2..93
FT                   /note="Muconolactone Delta-isomerase"
FT                   /id="PRO_0000089336"
SQ   SEQUENCE   93 AA;  10912 MW;  555EA3E79749F887 CRC64;
     MALFHVRMDV AIPRDLDPKV RDETIAKEKA YSQELQRSGK WPEIWRIVGQ YSNISIFDVE
     SADELHEILW NLPLFPYMNI EIMPLTKHGS DVK