ID   Y593_PYRFU              Reviewed;         310 AA.
AC   Q8U378;
DT   26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=UPF0282 protein PF0593 {ECO:0000255|HAMAP-Rule:MF_01406};
GN   OrderedLocusNames=PF0593;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
CC   -!- SIMILARITY: Belongs to the UPF0282 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01406}.
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DR   EMBL; AE009950; AAL80717.1; -; Genomic_DNA.
DR   RefSeq; WP_011011712.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8U378; -.
DR   STRING; 186497.PF0593; -.
DR   EnsemblBacteria; AAL80717; AAL80717; PF0593.
DR   GeneID; 41712398; -.
DR   KEGG; pfu:PF0593; -.
DR   PATRIC; fig|186497.12.peg.622; -.
DR   eggNOG; arCOG00969; Archaea.
DR   HOGENOM; CLU_079268_0_0_2; -.
DR   OMA; YHYDHHT; -.
DR   OrthoDB; 36408at2157; -.
DR   PhylomeDB; Q8U378; -.
DR   Proteomes; UP000001013; Chromosome.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_01406; UPF0282; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR014426; UPF0282_hydrls.
DR   PANTHER; PTHR43546:SF4; PTHR43546:SF4; 1.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   PIRSF; PIRSF004944; UCP004944_hydrls; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..310
FT                   /note="UPF0282 protein PF0593"
FT                   /id="PRO_0000057636"
SQ   SEQUENCE   310 AA;  34921 MW;  997F51513AB50CD9 CRC64;
     MKIIPIASES LGVRSLAVFV KVGKRGILID PGAALGPKRY SLSPANSEMA ALQLARSKIQ
     EFAKKADVIT ISHYHYDHHT PFFEGIYESS SPEIAKELYS GKILLIKHPT QNINASQKRR
     AHEFLKNVEG IAKKIEYGDS KTFDFGDFKI EFSPPVPHGR EGSKLGFVVM VLIDDGKKSV
     IHASDTQLIN EKAVKWIIEK NPDLLIAGGP PTYLTHRVGN VRDIGRELIN RIINETNAEL
     IIDHHIVRDK GYEEFFNSLD KRPLTFAEFL GRENAPLEAY RKELHEFEKG KDVELPKGIV
     KFLKELGEQK