Y469_BACHK
ID Y469_BACHK Reviewed; 658 AA.
AC Q6HNQ4;
DT 18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Probable methyl-accepting chemotaxis protein BT9727_0469;
GN OrderedLocusNames=BT9727_0469;
OS Bacillus thuringiensis subsp. konkukian (strain 97-27).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=281309;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=97-27;
RX PubMed=16621833; DOI=10.1128/jb.188.9.3382-3390.2006;
RA Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D.,
RA Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C.,
RA Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A.,
RA Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R.,
RA Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M.,
RA Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B.,
RA Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R.,
RA Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L.,
RA Brettin T.S., Gilna P.;
RT "Pathogenomic sequence analysis of Bacillus cereus and Bacillus
RT thuringiensis isolates closely related to Bacillus anthracis.";
RL J. Bacteriol. 188:3382-3390(2006).
CC -!- FUNCTION: Chemotactic-signal transducers respond to changes in the
CC concentration of attractants and repellents in the environment,
CC transduce a signal from the outside to the inside of the cell, and
CC facilitate sensory adaptation through the variation of the level of
CC methylation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000305}.
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DR EMBL; AE017355; AAT62354.1; -; Genomic_DNA.
DR RefSeq; WP_000939028.1; NC_005957.1.
DR RefSeq; YP_034817.1; NC_005957.1.
DR AlphaFoldDB; Q6HNQ4; -.
DR SMR; Q6HNQ4; -.
DR EnsemblBacteria; AAT62354; AAT62354; BT9727_0469.
DR KEGG; btk:BT9727_0469; -.
DR PATRIC; fig|281309.8.peg.499; -.
DR HOGENOM; CLU_000445_107_19_9; -.
DR OMA; AHPTMKP; -.
DR Proteomes; UP000001301; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF103190; SSF103190; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane; Chemotaxis; Coiled coil; Membrane; Methylation; Transducer;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..658
FT /note="Probable methyl-accepting chemotaxis protein
FT BT9727_0469"
FT /id="PRO_0000394197"
FT TOPO_DOM 1..14
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..283
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 305..658
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 150..221
FT /note="Cache"
FT DOMAIN 301..353
FT /note="HAMP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT DOMAIN 372..622
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00284"
FT COILED 44..109
FT /evidence="ECO:0000255"
FT MOD_RES 368
FT /note="Glutamate methyl ester (Glu)"
FT /evidence="ECO:0000250"
FT MOD_RES 592
FT /note="Deamidated glutamine"
FT /evidence="ECO:0000250"
FT MOD_RES 592
FT /note="Glutamate methyl ester (Gln)"
FT /evidence="ECO:0000250"
FT MOD_RES 627
FT /note="Glutamate methyl ester (Glu)"
FT /evidence="ECO:0000250"
FT MOD_RES 634
FT /note="Glutamate methyl ester (Glu)"
FT /evidence="ECO:0000250"
SQ SEQUENCE 658 AA; 71649 MW; A22A970CBB20F847 CRC64;
MLQGKLRRSS LKAKLLVSFV IVLILPSIVI GWTSYQQAKT NFNETILQSA EDNVKILNNV
INKEIDSKKV DAVYFTKLFN GVSYGTDQLQ NVQNKLEEYN KLHPEIEAIY TGSSTGQFIQ
SPSIQMPDGY NPTERDWYKE AAKKSGEVVI TAPYKSSTTG NIVITIAKQN EDKSGVLGID
LIINDIVNTS KMVNIGKTGF VAIFDQSKHV IAHPTMKPGD KIEEKVEKEL YKQETGDFKF
KLDGDDRNIT FITNKQTGWK IAGIMPSKEI IEAANPIFYK TLTVIGISLI IGGVLIYFII
ASIISPLKQL VISSKKISEG DLTETITVHS KDEIGQLGES FNEMAASLHH VISNINTSAS
HVAASSEELT ASMKQTSEAT EQITQAIEQV SSGAEIQTKE VEEGATLLEG VTEGIQRVAD
SSSLVSTASM YTKKKAEDGG KLVEQTVNQM QLIHESVSQS DKVIVLLDDK SKQIGAILEV
IQHIAEQTNL LALNAAIEAA RAGEQGRGFA IVADEVRKLA EQSGQSSTEI GKLVKEIQFD
IKETVSSMKQ VGTEVQSGLV VANETKQSFA EILKSTDDTV VQIDNMVDVA KQMTVDARQV
SASINEIAAT IEENAASVQN IAGSSEEQLA SVDEINAAAV HLSQMAEELQ EMIGKFKV
