ID   Y396_MYCLE              Reviewed;         369 AA.
AC   Q57240;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Uncharacterized protein ML0396/ML2692;
GN   OrderedLocusNames=ML0396;
GN   and
GN   OrderedLocusNames=ML2692; ORFNames=B1620_F3_113, L222-ORF2;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8969512; DOI=10.1099/13500872-142-11-3147;
RA   Fsihi H., de Rossi E., Salazar L., Cantoni R., Labo M., Riccardi G.,
RA   Takiff H.E., Eiglmeier K., Bergh S., Cole S.T.;
RT   "Gene arrangement and organization in an approximately 76 kb fragment
RT   encompassing the oriC region of the chromosome of Mycobacterium leprae.";
RL   Microbiology 142:3147-3161(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SIMILARITY: Belongs to the myo-inositol 1-phosphate synthase family.
CC       {ECO:0000305}.
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DR   EMBL; U00015; AAC43244.1; -; Genomic_DNA.
DR   EMBL; L39923; AAB53124.1; -; Genomic_DNA.
DR   EMBL; AL583918; CAC29904.1; -; Genomic_DNA.
DR   EMBL; AL583926; CAC32224.1; -; Genomic_DNA.
DR   PIR; S72835; S72835.
DR   RefSeq; NP_301384.1; NC_002677.1.
DR   RefSeq; NP_302718.1; NC_002677.1.
DR   RefSeq; WP_010907708.1; NC_002677.1.
DR   AlphaFoldDB; Q57240; -.
DR   SMR; Q57240; -.
DR   STRING; 272631.ML0396; -.
DR   EnsemblBacteria; CAC29904; CAC29904; CAC29904.
DR   EnsemblBacteria; CAC32224; CAC32224; CAC32224.
DR   KEGG; mle:ML0396; -.
DR   KEGG; mle:ML2692; -.
DR   PATRIC; fig|272631.5.peg.5186; -.
DR   Leproma; ML0396; -.
DR   Leproma; ML2692; -.
DR   eggNOG; COG1260; Bacteria.
DR   HOGENOM; CLU_050011_0_0_11; -.
DR   OMA; GTKEWAD; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0004512; F:inositol-3-phosphate synthase activity; IEA:InterPro.
DR   GO; GO:0006021; P:inositol biosynthetic process; IEA:InterPro.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR   InterPro; IPR002587; Myo-inos-1-P_Synthase.
DR   InterPro; IPR017815; Myo-inos-1-P_Synthase_actino.
DR   InterPro; IPR013021; Myo-inos-1-P_Synthase_GAPDH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01658; Inos-1-P_synth; 1.
DR   PIRSF; PIRSF015578; Myoinos-ppht_syn; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR03450; mycothiol_INO1; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..369
FT                   /note="Uncharacterized protein ML0396/ML2692"
FT                   /id="PRO_0000195201"
SQ   SEQUENCE   369 AA;  40278 MW;  021667A6D5DF9C93 CRC64;
     MSEHNPAGAP GASTEVRVAI VGVGNCASSL VQGIEYYQNA DDTSTVPGLM HVRFGPYHVR
     DVKFVAAFDV DAKKVGVDLS DAIFTSENNT IKIADVPPTN VVVQRGPTLD GIGKYYTDTI
     ELSDVPPVDV VQALTEAKTD VLVSYLPVGS EEADKFYAQC AINARVAFVN ALPVFIASDP
     VWAKKFADAR VPIVGDDIKS QVGATITHRV MAKLFEDRGV QLDRTMQLNV GGNMDFLNML
     ERERVQSKKI SKTQAVTSNV HREFNTKDIH IGPSDHVGWL DDRKWAYVRL EGRGFGDVPL
     NLEYKLEVWD SPNSAGVIID AVRAAKIAKD RGIGGPVIPA SSYLMKSPPQ QLPDEIARAQ
     LEEFIIDTK