ID   Y338_TREPA              Reviewed;         162 AA.
AC   O83358;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Uncharacterized protein TP_0338;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0338;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65329.1; -; Genomic_DNA.
DR   PIR; H71337; H71337.
DR   RefSeq; WP_010881786.1; NC_021490.2.
DR   AlphaFoldDB; O83358; -.
DR   SMR; O83358; -.
DR   IntAct; O83358; 3.
DR   STRING; 243276.TPANIC_0338; -.
DR   EnsemblBacteria; AAC65329; AAC65329; TP_0338.
DR   GeneID; 57878868; -.
DR   KEGG; tpa:TP_0338; -.
DR   HOGENOM; CLU_104656_0_0_12; -.
DR   OMA; PEPYTEN; -.
DR   OrthoDB; 2040023at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..162
FT                   /note="Uncharacterized protein TP_0338"
FT                   /id="PRO_0000014245"
FT   TRANSMEM        53..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   162 AA;  18367 MW;  718126C5CCC91F32 CRC64;
     MARVYILFFS VFFVFPLFSE DAARDVEPSD APVPYEDTEF SLWQKELYRF EALSIGAFPI
     VTLLSFITYD IIRLIQQWST KPPTWWALII PGAELPPLST KERAIVFGVA VGISVTIGLI
     DVTYRAVKRA IHRRSLERSQ LVPDPIELVP LDSFVEGTDD ST