ID   Y327_STRP6              Reviewed;         229 AA.
AC   Q5XDQ1;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Uncharacterized membrane protein M6_Spy0327;
GN   OrderedLocusNames=M6_Spy0327;
OS   Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=286636;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-946 / MGAS10394;
RX   PubMed=15272401; DOI=10.1086/422697;
RA   Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E.,
RA   Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.;
RT   "Progress toward characterization of the group A Streptococcus metagenome:
RT   complete genome sequence of a macrolide-resistant serotype M6 strain.";
RL   J. Infect. Dis. 190:727-738(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000305}.
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DR   EMBL; CP000003; AAT86462.1; -; Genomic_DNA.
DR   RefSeq; WP_002985910.1; NC_006086.1.
DR   AlphaFoldDB; Q5XDQ1; -.
DR   SMR; Q5XDQ1; -.
DR   EnsemblBacteria; AAT86462; AAT86462; M6_Spy0327.
DR   KEGG; spa:M6_Spy0327; -.
DR   HOGENOM; CLU_058671_1_2_9; -.
DR   OMA; SHNAYAE; -.
DR   Proteomes; UP000001167; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006214; Bax_inhibitor_1-related.
DR   PANTHER; PTHR23291; PTHR23291; 1.
DR   Pfam; PF01027; Bax1-I; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..229
FT                   /note="Uncharacterized membrane protein M6_Spy0327"
FT                   /id="PRO_0000179115"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   229 AA;  24960 MW;  35B44292638D1063 CRC64;
     MNDHVIYTQS DVGLNQFFAK IYSLVGMGVG LSAFVSYLML YPFRENLISI LVNQPMIYYG
     AAIIELILVF VASGAARKNT PAALPIFLIY SALNGFTLSF IIVAYAQTTV FQAFLSSAAV
     FFAMSIIGVK TKRDMSGLRK AMFAALIGVV VASLINLFIG SGMMSYVISV ISVLIFSGLI
     ASDNQMIKRV YQATNGQVGD GWAVAMALSL YLDFINLFIS LLRIFGRND